Results 21 to 30 of about 20,359 (170)

The Journey of in vivo Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road

open access: yesFrontiers in Immunology, 2018
Dendritic cells (DCs) are recognized as highly potent antigen-presenting cells that are able to stimulate cytotoxic T lymphocyte (CTL) responses with antitumor activity.
Cleo Goyvaerts, Karine Breckpot
doaj   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte   +2 more
wiley   +1 more source

ProTides for Antiviral Activity Beyond Liver Cells

open access: yesChemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel   +5 more
wiley   +1 more source

Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7‐year longitudinal study based on proviral load

open access: yesVeterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Bovine leukaemia virus (BLV) infection remains a major problem for Japanese Black (Wagyu) cattle, and effective and sustainable control measures are essential to prevent its spread in breeding herds. This study aimed to monitor the BLV infection status of all cattle at a Japanese Black breeding farm in Kagoshima Prefecture, Japan ...
Makoto Kajisa   +9 more
wiley   +1 more source

Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture.

open access: yesPLoS Pathogens, 2016
Foamy viruses (FV) belong to the genus Spumavirus, which forms a distinct lineage in the Retroviridae family. Although the infection in natural hosts and zoonotic transmission to humans is asymptomatic, FVs can replicate well in human cells making it an ...
Grégory Effantin   +7 more
doaj   +1 more source

Investigation of the Seroprevalence of Lentivirus ovivismae and Lentivirus capartenc (Formerly Known as Maedi‐Visna and Caprine Arthritis‐Encephalitis Virus) Infections in Sheep and Goats in the Yozgat Region

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study conducted in the Yozgat region determined a prevalence of 6.35% for maedi‐visna in sheep and 17.5% for caprine arthritis encephalitis in goats, providing critical data for small ruminant health and disease management in the area. ABSTRACT Background Lentivirus ovivismae and Lentivirus capartenc (formerly maedi‐visna and caprine arthritis ...
Emre Sayar   +3 more
wiley   +1 more source

Extending the Targets for Coronavirus Antivirals Beyond That of Approved Drugs: Insights From Preclinical Research

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
Chemical structure of RIBOTAC inhibitor with metabolic handle binding as nucleotide analogue to SARS‐CoV‐2 RNA dependent RNA polymerase, its linker and the RNase L recruiter which binds RNase L monomers and mediates their dimerization that actives nuclease activity degrading the viral RNA.
Harald Brüssow
wiley   +1 more source

Prevalence of Human T Lymphotropic Virus Type 1 in Pregnant Women: a Narrative Review

open access: yesMedical Laboratory Journal, 2020
Background and Objectives: Human T lymphotropic virus type I (HTLV-I) is a virus of the Retroviridae family, which has infected more than 20 million people around the world. The study aimed to review the prevalence of HTLV infection in pregnant women.    
zeinab nazari   +2 more
doaj  

Vector‐borne diseases‐knowledge maps

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA)   +7 more
wiley   +1 more source

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