Results 11 to 20 of about 20,383 (169)

Influence of Immunogenetic Biomarkers in the Clinical Outcome of HTLV-1 Infected Persons

open access: yesViruses, 2019
Human T-lymphotropic virus 1, a member of the Retroviridae family, causes a neglected, silent, persistent infection affecting circa 5 to 10 million people around the world, with biology, immune pathology, clinical diseases, epidemiology, and laboratory ...
Antonio Carlos Rosário Vallinoto   +4 more
doaj   +1 more source

Relationships of gag-pol diversity between Ty3/Gypsy and Retroviridae LTR retroelements and the three kings hypothesis

open access: yesBMC Evolutionary Biology, 2008
Background The origin of vertebrate retroviruses (Retroviridae) is yet to be thoroughly investigated, but due to their similarity and identical gag-pol (and env) genome structure, it is accepted that they evolve from Ty3/Gypsy LTR retroelements the ...
Fares Mario A   +2 more
doaj   +1 more source

Morphologic Differentiation of Viruses beyond the Family Level

open access: yesViruses, 2014
Electron microscopy has been instrumental in the identification of viruses by being able to characterize a virus to the family level. There are a few cases where morphologic or morphogenesis factors can be used to differentiate further, to the genus ...
Cynthia S. Goldsmith
doaj   +1 more source

The Late Asymptomatic and Terminal Immunodeficiency Phases in Experimentally FIV-Infected Cats—A Long-Term Study

open access: yesViruses, 2023
Feline immunodeficiency virus (FIV) is a lentivirus in the family Retroviridae that infects domestic cats resulting in an immunodeficiency disease featuring a progressive and profound decline in multiple sets of peripheral lymphocytes. Despite compelling
Brian G. Murphy   +6 more
doaj   +1 more source

Endogenous retroviruses in fish genomes: from relics of past infections to evolutionary innovations?

open access: yesFrontiers in Microbiology, 2016
The increasing availability of fish genome sequences has allowed to gain new insights into the diversity and host distribution of retroviruses in fish and other vertebrates.
Magali Naville, Jean-Nicolas VOLFF
doaj   +1 more source

Cellular proteins as potential targets for antiretroviral therapy

open access: yesВопросы вирусологии, 2023
The review article conducts an in-depth analysis of information gleaned from a comprehensive literature search across Scopus, Web of Science, and MedLine databases.
Marina R. Bobkova
doaj   +1 more source

Influence of the amino-terminal sequence on the structure and function of HIV integrase

open access: yesRetrovirology, 2020
Background Antiretroviral therapy (ART) can mitigate the morbidity and mortality caused by the human immunodeficiency virus (HIV). Successful development of ART can be accelerated by accurate structural and biochemical data on targets and their responses
Grant Eilers   +7 more
doaj   +1 more source

Análise epidemiológica dos casos de Aids no Sudeste brasileiro de 2010 a 2019

open access: yesPoblación y Salud en Mesoamérica, 2021
Introdução: A epidemia de HIV e Aids representa um dos maiores problemas de saúde pública atualmente. No Brasil, estima-se que apenas 83 % das pessoas vivendo com HIV conhecem seu diagnóstico e somente 46 % possuem carga viral indetectável.
Isabela Martins Rodrigues   +6 more
doaj  

Genetic Modification of T Cells

open access: yesBiomedicines, 2016
Gene transfer technology and its application to human gene therapy greatly expanded in the last decade. One area of investigation that appears particularly promising is the transfer of new genetic material into T cells for the potential treatment of ...
Richard A. Morgan, Benjamin Boyerinas
doaj   +1 more source

A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly

open access: yesViruses, 2021
The small cellular molecule inositol hexakisphosphate (IP6) has been known for ~20 years to promote the in vitro assembly of HIV-1 into immature virus-like particles.
Martin Obr   +2 more
doaj   +1 more source

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