Results 51 to 60 of about 11,204 (215)
Metatranscriptomics Analysis Reveals Diverse Viral RNA in Cutaneous Papillomatous Lesions of Cattle
Evolutionary Bioinformatics, 2022 Bovine papillomavirus (BPV) is associated with bovine papillomatosis, a disease that forms benign warts in epithelial tissues, as well as malignant lesions.
Adriana O Fernandes +2 more
doaj +1 more source
The design of retroviral vectors used in the CAR‐T products, risk management, and future perspective
MedComm, Volume 6, Issue 2, February 2025.This article compares gamma retroviral and lentiviral vectors, discussing packaging systems and SIN vector design. It also covers risks of secondary malignancies linked to retroviral vectors and strategies to minimize them. The article explores the regulatory framework, safety monitoring, and future safety improvements for CAR‐T therapy, emphasizing a ...
Huifang Yin, Xuejing Wei
wiley +1 more source
Clinical and Translational Science, Volume 18, Issue 2, February 2025.ABSTRACT Since its initial discovery, HIV has infected more than 70 million individuals globally, leading to the deaths of 35 million. At present, the annual number of deaths has significantly decreased due to 75% of HIV‐positive individuals being on antiretroviral therapy.
Alberto Vegas Rodriguez +4 more
wiley +1 more source
Ciência Rural, 2011 O Vírus da leucemia felina (FeLV) pertence à família Retroviridae, gênero Gammaretrovirus. Diferentemente de outras retroviroses, uma parcela dos gatos jovens e adultos exposta ao FeLV não apresenta antigenemia/viremia, de acordo com as técnicas ...
Andreza Soriano Figueiredo +1 more
doaj +1 more source
Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions
Advanced Science, Volume 12, Issue 3, January 20, 2025.Live attenuated vaccines represent a delicate equilibrium between virulence and immunogenicity during adaptation. The process of animal adaptation involves artificial selection; therefore, adapted viruses exhibit decreased pathogenicity to their original hosts and increased pathogenicity to their adapted hosts.
Yan‐Dong Tang +3 more
wiley +1 more source
Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution
Current Protocols, Volume 4, Issue 12, December 2024.Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Francesco Costacurta +3 more
wiley +1 more source
Current Protocols, Volume 4, Issue 11, November 2024.Abstract Keratinocytes are the most abundant cell type in the human epidermis, the outermost layer of the skin. For years, primary human keratinocytes (HKs) have been used as a crucial tool for studying the pathogenesis of a wide range of skin‐related diseases.
Martina Bamundo +4 more
wiley +1 more source
Acta Médica Peruana, 2010 El virus linfotrópico humano tipo 1 (HTLV-1 [human T-lymphotropic virus]) es un retrovirus con amplia distribución mundial. Pertenece a la familia Retroviridae y a la subfamilia Oncovirinae.
Eduardo Gotuzzo Herencia +5 more
doaj
Worldwide molecular epidemiology of HIV
Revista de Saúde Pública, 2006 Human immunodeficiency virus (HIV) is the worldwide disseminated causative agent of acquired immunodeficiency syndrome (AIDS). HIV is a member of the Lentivirus genus of Retroviridae family and is grouped in two types named HIV-1 and HIV-2. These viruses
Henry I Z Requejo
doaj +1 more source
Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements
Current Protocols, Volume 4, Issue 11, November 2024.Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Stefanie Rauch +3 more
wiley +1 more source