Results 101 to 110 of about 161,769 (345)

From Cells to Virus Particles: Quantitative Methods to Monitor RNA Packaging

Viruses, 2016
In cells, positive strand RNA viruses, such as Retroviridae, must selectively recognize their full-length RNA genome among abundant cellular RNAs to assemble and release particles.
Mireia Ferrer, Simon Henriet, Célia Chamontin, Sébastien Lainé, Marylène Mougel   +4 more
doaj   +1 more source

Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets [PDF]

, 2018
BACKGROUND: Subcutaneous implantation of a macroencapsulated patch containing human allogenic islets has been successfully used to alleviate type 1 diabetes mellitus (T1DM) in a human recipient without the need for immunosuppression.
Crossan, Claire, Gianello, Pierre, Mourad, Nizar I., Scobie, Linda, Smith, Karen   +4 more
core   +1 more source

Retrovirus Infection and Retinoid [PDF]

, 2011
Human T cell leukemia virus type I (HTLV-I) is a human retrovirus that is an etiologic agent of adult T cell leukemia/lymphoma (ATL/ATLL) ( Hinuma et al., 1981, Uchiyama et al., 1977). Adult ATL/ATLL is an aggressive lymphoid neoplasm associated with human T-cell leukemia virus type 1 (HTLV-1) (Hinuma et al, 1982). ATL, the first human disease found to
Jun-ichi Miyatake, Masaya Kawauchi, Chikara Hirase, Yasuhiro Maeda, Terufumi Yamaguchi, Itaru Matsumura   +5 more
openaire   +3 more sources

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

Sensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He, Shanying Han, Xinghong Liu, Xiaotong Huang, Wen Yang, Xinghua Tang, Chuan Dong, Jiangang Fan   +7 more
wiley   +1 more source

Evaluation of Different Antiretroviral Drug Protocols on Naturally Infected Feline Immunodeficiency Virus (FIV) Cats in the late Phase of the Asymptomatic Stage of Infection

Viruses, 2012
The aim of this study was to evaluate the efficacy of the antiretrovirals: Zidovudine (ZDV) alone; ZDV +<em> </em>Recombinant Human Interferon<em>-</em>α<em> </em>(rHuIFN-α); ZDV +<em> </em>Lamivudine (3TC)
Paola B. Pisano, Nélida V. Gómez, María A. Gisbert, Adriana Suraniti, Graciela Mira, Víctor Castillo, Adriana Fontanals   +6 more
doaj   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Prevalence, Geographic Distribution, Risk Factors and Co-Infections of Feline Gammaherpesvirus Infections in Domestic Cats in Switzerland

Viruses, 2019
Recently, a gammaherpesvirus was described in domestic cats (FcaGHV1). The goal of the present study was to investigate the presence of FcaGHV1 in Swiss domestic cats and analyze potential risk factors.
Marilisa Novacco, Neda Ranjbar Kohan, Martina Stirn, Marina L. Meli, Adrian Alberto Díaz-Sánchez, Felicitas S. Boretti, Regina Hofmann-Lehmann   +6 more
doaj   +1 more source

Intramolecular integration within Moloney murine leukemia virus DNA [PDF]

, 1981
By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions.
Baltimore, David, Goff, Stephen P., Hoffmann, Joseph, Shoemaker, Charles   +3 more
core  

Design Principles of Nanosensors for Multiplex Detection of Contaminants in Food

Small, EarlyView.
This review discusses recent advancements in nanoparticle‐based nanosensors for multiplex detection of food contaminants, focusing on toxins and pathogens. It highlights the design principles, sensitivity, and selectivity of these sensors, offering insights into their practical applications for food safety monitoring and inspiring future innovations ...
Yang Zhang, Shipeng Gao, Haoran Li, Tianxi Yang, Kaiyi Zheng, Zhing Ming Guo, Jiyong Shi, Xiaowei Huang, Xiaobo Zou, Pierre Picchetti, Frank Biedermann   +10 more
wiley   +1 more source

Evaluation of T Cell Immunity against Human Cytomegalovirus: Impact on Patient Management and Risk Assessment of Vertical Transmission

Journal of Immunology Research, 2016
Cytomegalovirus (CMV) is one of the most common infectious agents, infecting the general population at an early age without causing morbidity most of the time.
Giulia Freer, Paola Quaranta, Mauro Pistello   +2 more
doaj   +1 more source