, 1991 Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
Levinsky, Norman G. +1 more
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Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone. [PDF]
, 1984 J G Hellerman +5 more
openalex +1 more source
Microbiology and Immunology, EarlyView.ABSTRACT It is believed that human endogenous retrovirus (HERV)‐W plays a fundamental role in multiple sclerosis (MS) pathogenesis, probably by inducing humoral and cellular immunopathological response. HERVs present regions of similarity to myelin oligodendrocyte glycoprotein (MOG) and therefore could induce autoimmunity through the mechanism of ...
Karin C. Garcia +11 more
wiley +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity [PDF]
, 1998 We have investigated the genetic circuitry underlying the determination of neuronal identity, using mammalian peripheral autonomic neurons as a model system.
Anderson, David J. +2 more
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Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control. [PDF]
, 1986 Richard A. Katz +3 more
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Aging Cell, EarlyView.Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi +6 more
wiley +1 more source
Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]
, 1988 Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H. +7 more
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hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan
Aging Cell, EarlyView.In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam +15 more
wiley +1 more source
Generation of Transgenic Mice to Evaluate Promoter Activity and Specificity of Two Human Endogenous Retrovirus Long Terminal Repeats = Untersuchungen zur Promotor-Aktivität und -Spezifität von zwei Long Terminal Repeats humaner endogener Retroviren in transgenen Mäusen [PDF]
, 2003 Generation of Transgenic Mice to Evaluate Promoter Activity and Specificity of two Human Endogenous Retrovirus Long Terminal Repeats Human Endogenous Retrovirus Long Terminal Repeats (HERV-LTRs) comprise 1.8% of the human genome (52.7 Mb).
Schönfeld, Regine Margarete
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