Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
S. Neil, Trinity M Zang, P. Bieniasz
semanticscholar +1 more source
Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti‐apoptotic proteins.
Yu Chen+8 more
wiley +1 more source
Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying Hypotheses
John M. Coffin
openalex +1 more source
Retrovirus-mediated immunosuppression. II. FeLV-UV alters in vitro murine T lymphocyte behavior by reversibly impairing lymphokine secretion. [PDF]
Charles G. Orosz+3 more
openalex +1 more source
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
Dong Niu+21 more
semanticscholar +1 more source
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Advances in the Study of Pluripotent Stem Cells in Livestock
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou+6 more
wiley +1 more source
Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus [PDF]
Mark A. Muesing+5 more
openalex +1 more source
Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]
Denner, Joachim+2 more
core +1 more source
Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang+23 more
wiley +1 more source