Results 161 to 170 of about 161,769 (345)

Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti‐apoptotic proteins.
Yu Chen   +8 more
wiley   +1 more source

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

open access: yesScience, 2017
Dong Niu   +21 more
semanticscholar   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

open access: yesCell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou   +6 more
wiley   +1 more source

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus [PDF]

open access: bronze, 1985
Mark A. Muesing   +5 more
openalex   +1 more source

Production and Functional Verification of 8‐Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)‐Edited Donor Pigs for Xenotransplantation

open access: yesCell Proliferation, EarlyView.
Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang   +23 more
wiley   +1 more source

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