Results 11 to 20 of about 161,769 (345)

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1980
Bernard J. Poiesz, Francis W. Ruscetti, Adi F. Gazdar, Paul A. Bunn, John D. Minna, Robert C. Gallo   +5 more
openalex   +2 more sources

Morphology and ultrastructure of retrovirus particles

AIMS Biophysics, 2015
Retrovirus morphogenesis entails assembly of Gag proteins and the viral genome on the host plasma membrane, acquisition of the viral membrane and envelope proteins through budding, and formation of the core through the maturation process. Although in both immature and mature retroviruses, Gag and capsid proteins are organized as paracrystalline ...
Joachim D. Mueller, Jessica L. Martin, Wei Zhang, Louis M. Mansky, Sheng Cao   +4 more
openaire   +5 more sources

Advanced baseline immunosuppression is associated with elevated levels of plasma markers of fungal translocation and inflammation in long-term treated HIV-infected Tanzanians

AIDS Research and Therapy, 2021
Background For over a decade, antiretroviral therapy (ART) in resource-limited countries was only recommended for patients with advanced HIV disease.
Godfrey Barabona, Macdonald Mahiti, Mako Toyoda, Doreen Kamori, Salim Masoud, George P. Judicate, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno   +8 more
doaj   +1 more source

HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev

Scientific Reports, 2022
During HIV infection, intron-containing viral mRNAs are exported from the cell nucleus to the cytoplasm to complete the replication cycle. Cellular restrictions on the export of incompletely spliced transcripts are overcome by a viral protein, Rev, and ...
Godfrey Dzhivhuho, Jordan Holsey, Ethan Honeycutt, Heather O’Farrell, David Rekosh, Marie-Louise Hammarskjold, Patrick E. H. Jackson   +6 more
doaj   +1 more source

Development and characterization of a panel of anti-idiotype antibodies to 1C10 that cross-neutralize HIV-1 subtype B viruses

Frontiers in Virology, 2022
The V3 loop of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) is one of the conserved immunogenic regions targeted by neutralizing antibodies (nAb).
Yu Kaku, Kaho Matsumoto, Takeo Kuwata, Hasan Md Zahid, Shashwata Biswas, Miroslaw K. Gorny, Shuzo Matsushita   +6 more
doaj   +1 more source

Functional analysis of a monoclonal antibody reactive against the C1C2 of Env obtained from a patient infected with HIV-1 CRF02_AG

Retrovirology, 2021
Background Recent data suggest the importance of non-neutralizing antibodies (nnAbs) in the development of vaccines against HIV-1 because two types of nnAbs that recognize the coreceptor binding site (CoRBS) and the C1C2 region mediate antibody-dependent
Hasan Md Zahid, Takeo Kuwata, Shokichi Takahama, Yu Kaku, Shashwata Biswas, Kaho Matsumoto, Hirokazu Tamamura, Shuzo Matsushita   +7 more
doaj   +1 more source

2020 AAFP Feline Retrovirus Testing and Management Guidelines

Journal of feline medicine and surgery, 2020
Clinical importance: Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections are found in cats worldwide. Both infections are associated with a variety of clinical signs and can impact quality of life and longevity.
S. Little, J. Levy, K. Hartmann, R. Hofmann-Lehmann, M. Hosie, G. Olah, K. Denis   +6 more
semanticscholar   +1 more source

Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine

Nature Communications, 2022
mRNA vaccines have been shown to prevent SARS-CoV-2 infection and reduce hospitalization and mortality rates. Here, the authors show evidence of long-term memory CD8 + T cells in individuals who received the BNT162b2 SARS-CoV-2 mRNA vaccine.
Nozomi Kuse, Yu Zhang, Takayuki Chikata, Hung The Nguyen, Shinichi Oka, Hiroyuki Gatanaga, Masafumi Takiguchi   +6 more
doaj   +1 more source

Determinants and Mechanisms of the Low Fusogenicity and High Dependence on Endosomal Entry of Omicron Subvariants

mBio, 2023
The rapid spread and strong immune evasion of the SARS-CoV-2 Omicron subvariants has raised serious concerns for the global COVID-19 pandemic. These new variants exhibit generally reduced fusogenicity and increased endosomal entry pathway utilization ...
Panke Qu, John P. Evans, Chaitanya Kurhade, Cong Zeng, Yi-Min Zheng, Kai Xu, Pei-Yong Shi, Xuping Xie, Shan-Lu Liu   +8 more
doaj   +1 more source

Comparative virology of HTLV-1 and HTLV-2

Retrovirology, 2019
Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis.
Michael P. Martinez, Jacob Al-Saleem, Patrick L. Green   +2 more
doaj   +1 more source