Results 41 to 50 of about 124,737 (275)

Remnants of an ancient deltaretrovirus in the genomes of horseshoe aats (Rhinolophidae) [PDF]

, 2018
Endogenous retrovirus (ERV) sequences provide a rich source of information about the long-term interactions between retroviruses and their hosts. However, most ERVs are derived from a subset of retrovirus groups, while ERVs derived from certain other ...
Benda, Petr, Elleder, Daniel, Farkašová, Helena, Gifford, Robert J., Görföl, Tamás, Hron, Tomáš, Hulva, Pavel, Pačes, Jan   +7 more
core   +2 more sources

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas, Hoelzer, Dieter (Prof. Dr.), Hummel, Michael, Schwartz, Stefan, Thiel, Eckhard   +4 more
core   +2 more sources

Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]

, 2017
BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi, Bittmann, Claire Crossan, Clemenceau, Clemenceau, Cooper, Denner, Denner, Denner, Dieckhoff, Fishman, Gazda, Guo, Irgang, Kimsa, Korbutt, Linda Scobie, Matsumoto, Mazurek, Moon, Morozov, Mourad, Mueller, Nizar I. Mourad, Patience, Pierre Gianello, Pizzato, Schuurman, Scobie, Spizzo, Sypniewski, Tacke, Tucker, Victoria Cruikshank, Wynyard, Wynyard, Zhang   +36 more
core   +1 more source

The Role of Plasmacytoid Dendritic Cells in Innate and Adaptive Immune Responses against Alpha Herpes Virus Infections

Advances in Virology, 2011
In 1999, two independent groups identified plasmacytoid dendritic cells (PDC) as major type I interferon- (IFN-) producing cells in the blood. Since then, evidence is accumulating that PDC are a multifunctional cell population effectively coordinating ...
Philipp Schuster, Jan Bernardin Boscheinen, Karin Tennert, Barbara Schmidt   +3 more
doaj   +1 more source

RNA-Binding Domains of Heterologous Viral Proteins Substituted for Basic Residues in the RSV Gag NC Domain Restore Specific Packaging of Genomic RNA

Viruses, 2020
The Rous sarcoma virus Gag polyprotein transiently traffics through the nucleus, which is required for efficient incorporation of the viral genomic RNA (gRNA) into virus particles.
Breanna L. Rice, Timothy L. Lochmann, Leslie J. Parent   +2 more
doaj   +1 more source

Amplification of simian retroviral sequences from human recipients of baboon liver transplants [PDF]

, 1998
Investigations into the use of baboons as organ donors for human transplant recipients, a procedure called xenotransplantation, have raised the specter of transmitting baboon viruses to humans and possibly establishing new human infectious diseases ...
Anonymous, ANTHONY G. COMUZZIE, EVELYN M. WHITEHEAD, JONATHAN S. ALLAN, KAREN L. LEIGHTON, M. MICHELLE LELAND, MARIAN G. MICHAELS, ROBERT E. LANFORD, SUZANNE R. BROUSSARD, THOMAS E. STARZL, van der Kuyl AC, WALID HENEINE, WILLIAM M. SWITZER   +12 more
core   +1 more source

Tumorigenesis related to retroviral infections

Journal of Infection in Developing Countries, 2011
Retroviral infections are considered important risk factors for cancer development in humans since approximately 15-20% of cancer worldwide is caused by an infectious agent.
Maria Braoudaki, Fotini Tzortzatou-Stathopoulou   +1 more
doaj   +1 more source

Screening donors for xenotransplantation: The potential for xenozoonoses [PDF]

, 1994
Xenotransplantation is a potential solution to the current donor shortage for solid organ transplantation. The transmission of infectious agents from donor organs or bone marrow to the recipient is a well-recognized phenomenon following ...
Kahleen, B, Kalter, S, McMichael, JP, Michaels, MG, Peters, RL, Simmons, RL, Starzl, TE   +6 more
core   +1 more source

Investigation of the activity of phosphothioate and phosphothioate-LNA-modified oligonucleotides against HIV-1

Frontiers in Medicine
This study investigated the antiretroviral efficacy, toxicity profile, and cellular uptake of phosphothioate (PS) and PS/LNA-modified oligonucleotides within an in vitro HIV infection model.
Ludmila Gotfrid, Kirill Elfimov, Maria Gashnikova, Aleksey Totmenin, Aleksandr Agaphonov, Natalya Gashnikova   +5 more
doaj   +1 more source

Blocking Type I Interferon Production: A New Therapeutic Option to Reduce the HIV-1-Induced Immune Activation

Clinical and Developmental Immunology, 2012
Highly active antiretroviral therapy has dramatically improved the morbidity and mortality of HIV-1-infected individuals. A total of 25 licensed drugs provide the basis for an optimized virus-suppressive treatment of nearly each subject.
Moritz Ries, Kathrin Pritschet, Barbara Schmidt   +2 more
doaj   +1 more source