Results 51 to 60 of about 1,333,888 (286)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rotational Heisenberg Inequalities [PDF]

, 2015
Since their discovery in 1927, the Heisenberg Inequalities have become an icon of quantum mechanics. Often inappropriately referred to as the Uncertainty Principle, these inequalities relating the standard deviations of the position and momentum ...
Ansermet, Jean-Philippe, Brechet, Sylvain D., Maschke, Klaus, Reuse, Francois A.   +3 more
core   +1 more source

Separating Use and Reuse to Improve Both [PDF]

, 2019
Context: Trait composition has inspired new research in the area of code reuse for object oriented (OO) languages. One of the main advantages of this kind of composition is that it makes possible to separate subtyping from subclassing; which is good for ...
Arora, Hrshikesh, Oliveira, Bruno C. D. S., Servetto, Marco   +2 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The influencing mechanism of manufacturing scene change on process domain knowledge reuse [PDF]

, 2013
It is necessary for a enterprise to reuse outside process domain knowledge to develop intelligent manufacturing technology. The key factors influencing knowledge reuse in digital manufacturing scene are manufacturing activities and PPR (Products ...
Ling, Tiezhang, Liu, Chuang, Wang, Junbiao   +2 more
core  

Legislation for the Reuse of Biosolids on Agricultural Land in Europe: Overview

Sustainability, 2019
The issues concerning the management of sewage sludge produced in wastewater treatment plants are becoming more important in Europe due to: (i) the modification of sludge quality (biological and chemical sludge are often mixed with negative impacts on ...
M. Collivignarelli, A. Abbá, Andrea Frattarola, M. Carnevale Miino, S. Padovani, I. Katsoyiannis, V. Torretta   +6 more
semanticscholar   +1 more source

Components reuse in the building sector – A systematic review

Waste Management Research, 2020
Widespread reuse of building components can promote the circularity of materials in the building sector. However, the reuse of building components is not yet a mainstream practise.
Kambiz Rakhshan, J. Morel, H. Alaka, R. Charef   +3 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Revealing the Effects of Powder Reuse for Selective Laser Melting by Powder Characterization

JOM, 2019
In a selective laser melting process, it is common to reuse the powder in consecutive cycles of the route because it is more sustainable and cost effective. However, it is unknown whether reusing the material has an influence on the process.
L. Cordova, M. Campos, T. Tinga
semanticscholar   +1 more source