Results 61 to 70 of about 4,155 (132)

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Electrocatalytically Amplified Immunosensing Enabled by Titanium Oxynitride‐Supported Ru Nanodots on Graphene Oxide Hybrid Architecture

Small, EarlyView.
A synergistic effect among the electrocatalytic Ru/TiON‐GO nanocomposite, biorecognition elements, and the [Fe(CN)6]3−/4− redox probe for highly sensitive and selective impedimetric detection of PSA protein in human serum was demonstrated. The immunosensor exhibited a limit of detection of only 0.06 ng mL−1 PSA protein, underscoring the importance and ...
Mitja Koderman, Milutin Smiljanić, Filip Cernatič, Marjan Bele, Francisco Ruiz‐Zepeda, Nejc Hodnik, Mitja Kolar, Samo B. Hočevar, Nikola Tasić   +8 more
wiley   +1 more source

REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6

Biology Open, 2017
The circadian clock contributes to the timing of many body functions including metabolism and reproduction. The hepatokine fibroblast growth factor 21 (FGF21) is a critical metabolic regulator involved in modulation of fertility.
Rohit Chavan, Nadia Preitner, Takashi Okabe, Laureen Mansencal Strittmatter, Cheng Xu, Jürgen A. Ripperger, Nelly Pitteloud, Urs Albrecht   +7 more
doaj   +1 more source

Unraveling the Electrocatalytic Performance and Structural Stability of Ag Nanowire Gas Diffusion Electrodes for CO2 Reduction

ChemSusChem, Volume 19, Issue 15, 14 August 2026.
Silver nanowires (AgNWs) catalyze CO2 reduction into CO with high selectivity both in the three‐electrode cell and in the zero‐gap electrolyzer. While catalytic currents and selectivity are stable over hours, the AgNW shape undergoes restructuring and its surface chemistry changes.
Ola Bajouk, Bhavani Ravi, Elhassan Amaterz, Sophie Depriester, Isabelle Rougeaux, Dmitry Aldakov, Bertrand Reuillard, Pascale Chenevier   +7 more
wiley   +1 more source

Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription1

Journal of Lipid Research, 2002
Elevated serum levels of triglyceride-rich remnant lipoproteins (TRL) are a major risk factor predisposing a subject to atherosclerosis. Apolipoprotein C-III (apoC-III) is a major constituent of TRL that impedes triglyceride hydrolysis and remnant ...
Eric Raspé, Hélène Duez, Anethe Mansén, Coralie Fontaine, Catherine Fiévet, Jean-Charles Fruchart, Bjorn Vennström, Bart Staels   +7 more
doaj   +1 more source

Unraveling the Role of Lignin Oligomers Functionality for the Synthesis of Nonisocyanate Polyurethanes

ChemSusChem, Volume 19, Issue 15, 14 August 2026.
This study reports the synthesis of bio‐based nonisocyanate polyhydroxyurethanes from crude lignins and depolymerized lignin oligomers. The structure–properties relationships were largely explored and highlighted the key role of lignin functionality on the physical properties of the materials. Lignins are the main source of aromatic compounds in nature.
Nathan Wybo, Hugo Lilti, Dorothée Laurenti, Christophe Geantet, Antoine Duval, Luc Avérous   +5 more
wiley   +1 more source

Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.

PLoS Biology, 2018
Circadian clocks are fundamental physiological regulators of energy homeostasis, but direct transcriptional targets of the muscle clock machinery are unknown.
Kenneth Allen Dyar, Michaël Jean Hubert, Ashfaq Ali Mir, Stefano Ciciliot, Dominik Lutter, Franziska Greulich, Fabiana Quagliarini, Maximilian Kleinert, Katrin Fischer, Thomas Oliver Eichmann, Lauren Emily Wright, Marcia Ivonne Peña Paz, Alberto Casarin, Vanessa Pertegato, Vanina Romanello, Mattia Albiero, Sara Mazzucco, Rosario Rizzuto, Leonardo Salviati, Gianni Biolo, Bert Blaauw, Stefano Schiaffino, N Henriette Uhlenhaut   +22 more
doaj   +1 more source

Investigating the Direct Use of Manganese‐Rich Mixed‐Olivine Cathode in Sodium Battery

Batteries &Supercaps, Volume 9, Issue 8, August 2026.
Electrochemically driven Li+/Na+ ion exchange enables the direct use of Li‐based LMFP in Na‐metal cells. Operando/ex situ XAS and PXRD reveal the progressive transformation from LMFP to Na‐triphylite NMFP during cycling. The resulting sodium‐based phase exhibits stable electrochemical performance and compatibility with safer polymer‐electrolyte Na ...
Luca Minnetti, Mariam Maisuradze, Asia Patriarchi, Min Li, Leonardo Sbrascini, Zulkarnaen Paputungan, Paolo Conti, Francesco Nobili, Marco Giorgetti   +8 more
wiley   +1 more source

Rev-erbs and Glia—Implications for Neurodegenerative Diseases

Journal of Experimental Neuroscience, 2019
Recently, we described a role for the circadian clock protein and nuclear receptor Rev-erbα in regulating glial activation states in the brain. Deletion of Rev-erbα resulted in microglial as well as astrocytic activation, while a Rev-erbα agonist ...
Percy Griffin, Julie M Dimitry, Erik S Musiek   +2 more
doaj   +1 more source

Potent Therapeutic Insights From Eryngium campestre: Phytochemical Profiling and In Vitro Evaluation

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The phytochemical profiles and biological activity of ethyl acetate, ethanol, ethanol‐water, and water extracts of Eryngium campestre were assessed. E. campestre is a prospective source of multifunctional bioactive chemicals for food and nutraceutical uses, as demonstrated by the extracts' potential antioxidant, enzyme‐inhibitory, anticancer ...
Kübra Seyhan, Gamze Akıllı, Pınar Baloglu, Ayşenur Özdemir Kanat, Nurdan Tugba Iscen, Giovanni Caprioli, Agnese Santanatoglia, Massimo Ricciutelli, Mehmet Cengiz Baloglu, Yasemin Celik Altunoglu, Muammer Bahsi, Milena Terzic, Gökhan Zengin   +12 more
wiley   +1 more source