Results 71 to 80 of about 57,909 (296)
Prefrontal-inferotemporal interaction is not always necessary for reversal learning. [PDF]
, 2008 Prefrontal cortex (PFC) is thought to have a wide-ranging role in cognition, often described as executive function or behavioral inhibition. A specific example of such a role is the inhibition of representations in more posterior regions of cortex in a ...
Wilson, CR, Gaffan, David, Gaffan, D
core +3 more sources
Frontiers in Behavioral Neuroscience, 2019 Dementia and cognitive decline have become worldwide health problems due to rapid growth of the aged population in many countries. We previously demonstrated that single or short-term administration of iso-α-acids, hop-derived bitter acids in beer ...
Tatsuhiro Ayabe, Rena Ohya, Yasuhisa Ano
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
eLife, 2021 Inhibitory interneurons are believed to realize critical gating functions in cortical circuits, but it has been difficult to ascertain the content of gated information for well-characterized interneurons in primate cortex.
Kianoush Banaie Boroujeni +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Explaining reversal learning deficits in anxiety with electrophysiological evidence [PDF]
, 2023 Reversal learning is a crucial aspect of behavioral flexibility that plays a significant role in environmental adaptation and development. While previous studies have established a link between anxiety and impaired reversal learning ability, the ...
Gu, Ruolei +11 more
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Frontiers in Pediatrics, 2020 Neonatal hypoxic-ischemic encephalopathy (HIE) remains a common problem world-wide for infants born at term. The impact of HIE on long-term outcomes, especially into adulthood, is not well-described.
Jessie R. Maxwell +11 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Rapid Cue Reversal Learning [PDF]
, 2015 Excerpt: Rapid cue reversal learning refers to the ability to alter one’s response after encountering just a few examples of a change in consequences for a behavior.
Lionello-DeNolf, Karen M.
core +1 more source
Subcortical Dopamine and Cognition in Schizophrenia: Looking Beyond Psychosis in Preclinical Models
Frontiers in Neuroscience, 2020 Schizophrenia is characterized by positive, negative and cognitive symptoms. All current antipsychotic treatments feature dopamine-receptor antagonism that is relatively effective at addressing the psychotic (positive) symptoms of schizophrenia. However,
Kyna-Anne Conn +4 more
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