Results 51 to 60 of about 57,909 (296)
Induced Positive Mood and Cognitive Flexibility: Evidence from Task Switching and Reversal Learning
Collabra: Psychology, 2018 Positive mood often facilitates cognitive functions. Facilitation is hypothesized to be due to an increase in dopamine occurring in positive mood states. However, facilitation has not been consistently found in studies of cognitive flexibility.
Amy T. Nusbaum +4 more
doaj +1 more source
Reversal learning reliability behavioural dataset [PDF]
, 2023 This repository contains re-test data for a reversal learning task completed by 150 participants, and associated scripts for the analysis of the reliability of behavioural and computational model parameters.
Brady, Daniel +2 more
core +1 more source
Cell Reports, 2016 Neural circuits involving midbrain dopaminergic (DA) neurons regulate reward and goal-directed behaviors. Although local GABAergic input is known to modulate DA circuits, the mechanism that controls excitatory/inhibitory synaptic balance in DA neurons ...
Sarah X. Luo +8 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The use of signs to facilitate maze learning in dairy cows (Bos taurus). [PDF]
, 2009 Little is known about whether or not cows can learn to use a visual cue to navigate complex paths. Experiment 1 investigated discrimination learning of dairy cows where the discrimination problems involved selecting a signalled one-way pair of gates in ...
Blackmore, Tania Louise
core
An associative account of collective learning
Royal Society Open ScienceAssociative learning is an important adaptive mechanism that is well conserved among a broad range of species. Although it is typically studied in isolated animals, associative learning can occur in the presence of conspecifics in nature.
Matthew Gildea +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source