Tuning a binary ferromagnet into a multi-state synapse with spin-orbit torque induced plasticity [PDF]
, 2016 Inspired by ion-dominated synaptic plasticity in human brain, artificial synapses for neuromorphic computing adopt charge-related quantities as their weights.
Cao, Yi +4 more
core +4 more sources
Learning reversible symplectic dynamics
, 2022 Time-reversal symmetry arises naturally as a structural property in many dynamical systems of interest. While the importance of hard-wiring symmetry is increasingly recognized in machine learning, to date this has eluded time-reversibility. In this paper we propose a new neural network architecture for learning time-reversible dynamical systems from ...
Valperga, R +4 more
openaire +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A reversal coarse-grained analysis with application to an altered functional circuit in depression [PDF]
, 2013 Introduction: When studying brain function using functional magnetic resonance imaging (fMRI) data containing tens of thousands of voxels, a coarse-grained approach – dividing the whole brain into regions of interest – is applied frequently to ...
Feng, Jianfeng +3 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood [PDF]
, 2016 Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Dwoskin, Linda P. +3 more
core +1 more source
Clarifying the neural substrates of threat and safety reversal learning in humans
NeuroImage, 2019 Responding flexibly to sources of threat and safety is critical to the adaptive regulation of emotions, including fear. At a neural systems level, such flexibility is thought to rely on an extended neural circuitry involving the dorsal anterior cingulate
Hannah S. Savage +3 more
semanticscholar +1 more source
Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas +7 more
wiley +1 more source
Contributions of anterior cingulate cortex and basolateral amygdala to decision confidence and learning under uncertainty. [PDF]
, 2019 The subjective sense of certainty, or confidence, in ambiguous sensory cues can alter the interpretation of reward feedback and facilitate learning. We trained rats to report the orientation of ambiguous visual stimuli according to a spatial stimulus ...
Hart, EE +7 more
core +1 more source
A language-familiarity effect for speaker discrimination without comprehension [PDF]
, 2014 The influence of language familiarity upon speaker identification is well established, to such an extent that it has been argued that “Human voice recognition depends on language ability” [Perrachione TK, Del Tufo SN, Gabrieli JDE (2011) Science 333(6042)
Belin, Pascal +3 more
core +5 more sources