Results 51 to 60 of about 124,891 (298)

An apolipoprotein A-I mimetic dose-dependently increases the formation of preβ1 HDL in human plasma

Journal of Lipid Research, 2008
Preβ1 HDL is the initial plasma acceptor of cell-derived cholesterol in reverse cholesterol transport. Recently, small amphipathic peptides composed of D-amino acids have been shown to mimic apolipoprotein A-I (apoA-I) as a precursor for HDL formation ...
Jason S. Troutt, William E. Alborn, Marian K. Mosior, Jiannong Dai, Anthony T. Murphy, Thomas P. Beyer, Youyan Zhang, Guoqing Cao, Robert J. Konrad   +8 more
doaj   +1 more source

Pancreas transplantation modulates reverse cholesterol transport [PDF]

Transplant International, 1999
Hyperinsulinemia secondary to insulin resistance in type-II diabetes or in the metabolic syndrome is associated with the "atherogenetic lipoprotein phenotype": high triglycerides, small, dense low-density lipoprotein (LDL) cholesterol, and low high-density lipoprotein (HDL) cholesterol.
B, Föger, A, Königsrainer, A, Ritsch, M, Lechleitner, W, Steurer, R, Margreiter, J R, Patsch   +6 more
openaire   +2 more sources

The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAs

Biology, 2015
MicroRNAs (miRNAs) are small, non-coding RNAs that have the ability to post-transcriptionally regulate gene expression. Hundreds of miRNAs have been identified in humans and they are involved in the regulation of almost every process, including ...
Diana M. DiMarco, Maria Luz Fernandez
doaj   +1 more source

Effects of flavonoids on cholesterol efflux capability

International Journal of Medical Biochemistry, 2022
Reverse cholesterol transport (RCT), which plays a critical role in the export of cholesterol from peripheral cells, is one of the processes employed in the management and treatment of atherosclerosis.
Maha Abdulmajeed Ayoub
doaj   +1 more source

Tachometer for Reverse Cholesterol Transport? [PDF]

Journal of the American Heart Association, 2012
Many clinical and epidemiological studies, as well as meta-analyses thereof, have shown the inverse relationship of high-density lipoprotein cholesterol (HDL-C) and apoliopoprotein (apo) A-I plasma levels with the risk of coronary artery disease.[1][1] HDL particles and their protein and ...
openaire   +3 more sources

Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity

Journal of Lipid Research, 2009
The main antiatherogenic function of HDL is to promote the efflux of cholesterol from peripheral cells and transport it to the liver for excretion in a process termed reverse cholesterol transport.
Shuhei Nakanishi, Riikka Vikstedt, Sanni Söderlund, Miriam Lee-Rueckert, Anne Hiukka, Christian Ehnholm, Mikko Muilu, Jari Metso, Jussi Naukkarinen, Leena Palotie, Petri T. Kovanen, Matti Jauhiainen, Marja-Riitta Taskinen   +12 more
doaj   +1 more source

Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury

Research, 2023
Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered a barrier for regeneration in the central nervous system.
Bolin Zheng, Yijing He, Shuai Yin, Xu Zhu, Qing Zhao, Huiyi Yang, Zhaojie Wang, Rongrong Zhu, Liming Cheng   +8 more
doaj   +1 more source

The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican Health Study*[S]

Journal of Lipid Research, 2009
Low HDL-cholesterol (HDL-C) is associated with an increased risk for atherosclerosis, and concentrations are modulated by genetic factors and environmental factors such as smoking.
Mireia Junyent, Katherine L. Tucker, Caren E. Smith, Antonio Garcia-Rios, Josiemer Mattei, Chao-Qiang Lai, Laurence D. Parnell, Jose M. Ordovas   +7 more
doaj   +1 more source

Physical Fitness and Reverse Cholesterol Transport [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
Background— Physical exercise is associated with a decreased risk of cardiovascular disease, which may be partly caused by the effect of exercise on the lipoprotein profile. The most consistent effect of exercise on lipoprotein metabolism is an increase in high-density lipoprotein (HDL).
Beata, Olchawa, Bronwyn A, Kingwell, Anh, Hoang, Laurence, Schneider, Osamu, Miyazaki, Paul, Nestel, Dmitri, Sviridov   +6 more
openaire   +2 more sources

ABCA1: the gatekeeper for eliminating excess tissue cholesterol

Journal of Lipid Research, 2001
It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing excess cholesterol from arterial cells.
John F. Oram, Richard M. Lawn
doaj   +1 more source