Results 31 to 40 of about 144,135 (296)

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

open access: yes, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Adachi Y   +48 more
core   +1 more source

An apolipoprotein A-I mimetic dose-dependently increases the formation of preβ1 HDL in human plasma

open access: yesJournal of Lipid Research, 2008
Preβ1 HDL is the initial plasma acceptor of cell-derived cholesterol in reverse cholesterol transport. Recently, small amphipathic peptides composed of D-amino acids have been shown to mimic apolipoprotein A-I (apoA-I) as a precursor for HDL formation ...
Jason S. Troutt   +8 more
doaj   +1 more source

Cyclosporine A impairs the macrophage reverse cholesterol transport in mice by reducing sterol fecal excretion. [PDF]

open access: yesPLoS ONE, 2013
Despite the efficacy in reducing acute rejection events in organ transplanted subjects, long term therapy with cyclosporine A is associated with increased atherosclerotic cardiovascular morbidity.
Ilaria Zanotti   +7 more
doaj   +1 more source

Pancreas transplantation modulates reverse cholesterol transport [PDF]

open access: yesTransplant International, 1999
Hyperinsulinemia secondary to insulin resistance in type-II diabetes or in the metabolic syndrome is associated with the "atherogenetic lipoprotein phenotype": high triglycerides, small, dense low-density lipoprotein (LDL) cholesterol, and low high-density lipoprotein (HDL) cholesterol.
B, Föger   +6 more
openaire   +2 more sources

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

open access: yes, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Groen, A.K.   +3 more
core   +3 more sources

Cholesterol and Lipoprotein Metabolism and Atherosclerosis: Recent Advances in Reverse Cholesterol Transport

open access: yesAnnals of Hepatology, 2017
Atherosclerosis is characterized by lipid accumulation, inflammatory response, cell death and fibrosis in the arterial wall, and is a major pathological basis for ischemic coronary heart disease (CHD), which is the leading cause of morbidity and ...
Helen H. Wang   +4 more
doaj   +1 more source

Tachometer for Reverse Cholesterol Transport? [PDF]

open access: yesJournal of the American Heart Association, 2012
Many clinical and epidemiological studies, as well as meta-analyses thereof, have shown the inverse relationship of high-density lipoprotein cholesterol (HDL-C) and apoliopoprotein (apo) A-I plasma levels with the risk of coronary artery disease.[1][1] HDL particles and their protein and ...
openaire   +3 more sources

The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAs

open access: yesBiology, 2015
MicroRNAs (miRNAs) are small, non-coding RNAs that have the ability to post-transcriptionally regulate gene expression. Hundreds of miRNAs have been identified in humans and they are involved in the regulation of almost every process, including ...
Diana M. DiMarco, Maria Luz Fernandez
doaj   +1 more source

Effects of flavonoids on cholesterol efflux capability

open access: yesInternational Journal of Medical Biochemistry, 2022
Reverse cholesterol transport (RCT), which plays a critical role in the export of cholesterol from peripheral cells, is one of the processes employed in the management and treatment of atherosclerosis.
Maha Abdulmajeed Ayoub
doaj   +1 more source

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