FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Output performance of Bi-Sb-Te based thermoelectric-transistor model on parallel temperature gradient. [PDF]
Sci RepGuo T +6 more
europepmc +1 more source
REVERSE TIME TLM MODELING OF THERMAL PROBLEMS DESCRIBED BY THE HYPERBOLIC HEAT CONDUCTION EQUATION
, 2003 A. L. Koay, S.H. Pulko, A.J. Wilkinson
openalex +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Pacing-Induced Cardiomyopathy in a Transplanted Heart Treated With Left Bundle Branch Pacing. [PDF]
JACC Case RepTomassoni N +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Investigation of electrical transport mechanisms in an n-CdIn<sub>2</sub>Se<sub>4</sub>/Pt thin film Schottky diode fabricated by pulsed laser deposition. [PDF]
RSC AdvDhruv SD +10 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
In Situ Scanning Transmission Electron Microscopy/Transmission Electron Microscopy Study of Defect-Driven Ag Ion Dynamics and Filament Evolution in CuO Nanowire-Based Memristors. [PDF]
ACS Appl Mater InterfacesHung CH, Chi CC, Hsiao KY, Lu MY.
europepmc +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source