Results 81 to 90 of about 50,432 (316)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Faster Time Response by the Use of Wire Electrodes in Capacitive Salinity Gradient Energy Systems [PDF]

, 2012
Capacitive energy extraction based on Donnan potential (CDP) and capacitive energy extraction based on double layer expansion (CDLE) are novel electroctrochemical processes to convert the potential free energy of mixing sea and river water into electric ...
Sales, Bruno B, Schaetzle, Olivier, Schaetzle, O., Liu, Fei, Buisman, Cees JN, Sales, B.B., Hamelers, Hubertus VM, Burheim, O.S., Burheim, Odne S, Hamelers, H.V.M., Liu, F., Buisman, C.J.N.   +11 more
core   +1 more source

Properly Conducted Fundoplication Reverses Histologic Evidence Of Esophagitis

Annals of Surgery, 1983
Little is known about the fate of histologic changes of esophagitis following an antireflux procedure. In a widely quoted paper (Gastroenterology 1979; 76:1393), initial healing of esophagitis was reported, but it was noted that normal biopsies reversed to abnormal in a small number of patients who were followed for up to 69 months. The authors studied
J D, Richardson, J G, Kuhns, R L, Richardson, H C, Polk   +3 more
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Experimental research on factors influencing the current commutation process of variable-polarity arc welding

工程科学学报, 2019
In the current inversion process of variable-polarity arc welding of aluminum alloy, drastic changes in electron and ion concentrations in arc space may lead to the failure of current commutation and arc reignition, thus affecting the arc burning ...
ZHU Zhi-ming, FU Ping-po, YANG Zhong-yu, XIA Zhu-liang, CHENG Shi-jia   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Continuous-conduction-mode SEPIC converter with low reverse-recovery loss for power factor correction [PDF]

, 2019
A continuous-conduction-mode SEPIC converter with low reverse-recovery loss is proposed for power factor correction. The proposed SEPIC converter can reduce the reverse-recovery loss of the diodes and improve the power efficiency.
Kim, EH, Lee, JJ, Kwon, JM, Choi, WY, Kwon, BH   +4 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

An improved SiC SWITCH‐MOS with superior forward performance

IET Power Electronics
An improved 4H‐SiC SBD‐wall‐integrated trench metal‐oxide‐semiconductor (SWITCH‐MOS) with n‐bury and split‐gate is proposed. Under the premise of ensuring breakdown voltage (BV), the n‐bury layer can smooth the path to current conduction, which reduces ...
Junji Cheng, Tao Zhong, Huan Li, Ping Li, Bo Yi, Haimeng Huang, Siliang Wang, Qiang Hu, Hongqiang Yang   +8 more
doaj   +1 more source