Results 201 to 210 of about 666,471 (318)

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells [PDF]

, 2011
Ulrich Elling, Jasmin Taubenschmid, Gerald Wirnsberger, Ronan C. O’Malley, Simon-Pierre Demers, Quentin Vanhaelen, Andrey I. Shukalyuk, Gerald Schmauss, Daniel Schramek, Frank Schnuetgen, Harald von Melchner, Joseph R. Ecker, William L. Stanford, Johannes Zuber, Alexander Stark, Josef Penninger   +15 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Reverse genetics in the Arabidopsis chloroplast genome identifies rps16 as a transcribed pseudogene. [PDF]

Plant J
Ruf S, Trösch R, Schollbach L, Kroop X, Forner J, Gefen-Treves S, Henze A, Thiele W, Schöttler MA, Zoschke R, Bock R.   +10 more
europepmc   +1 more source

Infectious Subgenomic Amplicons method to expedite reverse genetics of SARS-CoV-2 and other coronaviruses

, 2020
Julien Mélade, Géraldine Piorkowski, Franck Touret, Toscane Fourié, Bruno Coutard, Antoine Nougaırède, Xavier de Lamballerie   +6 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Establishment of reverse genetics systems for Colorado tick fever virus. [PDF]

PLoS Pathog
Minami S, Nouda R, Hirai K, Chen Z, Kotaki T, Kanai Y, Kobayashi T.   +6 more
europepmc   +1 more source

Recent insights into reverse genetics of norovirus. [PDF]

Virus Res, 2023
Zhang Q, Zhu S, Zhang X, Su L, Ni J, Zhang Y, Fang L.   +6 more
europepmc   +1 more source

Congenital lipodystrophy induces severe osteosclerosis [PDF]

, 2019
Brestoff, Jonathan R, Brodt, Michael D, Craft, Clarissa S, Harris, Carles A, Migotsky, Nicole, Rohatgi, Nidhi, Scheller, Erica L, Silva, Matthew J, Teitelbaum, Steven L, Zhang, Yan, Zou, Wei   +10 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Interactome and reverse genetics studies of regulatory subunits of Plasmodium falciparum casein kinase [PDF]

, 2010
Guillem Dayer
openalex