Results 101 to 110 of about 1,758,180 (373)
Association of interferon-gamma release assay and SARS-CoV-2 reverse transcriptase polymerase chain reaction test results in adults tested in a tertiary medical center [PDF]
Lagamayo Evelina N +2 more
openalex +1 more source
Phenotypic hypersusceptibility to multiple protease inhibitors and low replicative capacity in patients who are chronically infected with human immunodeficiency virus type 1 [PDF]
Increased susceptibility to the protease inhibitors saquinavir and amprenavir has been observed in human immunodeficiency virus type 1 (HIV-1) with specific mutations in protease (V82T and N88S).
Clotet, B +7 more
core +2 more sources
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong +7 more
wiley +1 more source
The human T-lymphotropic virus type 1 (HTLV-1) infects millions of people globally and is endemic to various resource-limited regions. Infections persist for life and are associated with increased susceptibility to opportunistic infections and severe ...
Nicolas Tardiota +4 more
doaj +1 more source
The use of highly active antiretroviral therapy (HAART) involves combinations of drugs to achieve maximal virological response and reduce the potential for the emergence of antiviral resistance.
Mark A. Wainberg
doaj +1 more source
Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]
The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria +2 more
core +2 more sources
A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi +5 more
wiley +1 more source
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Telomerase, a unique reverse transcriptase that specifically extends the ends of linear chromosomes, is up-regulated in the vast majority of cancer cells.
Wilnelly Hernandez-Sanchez +8 more
doaj +1 more source
Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard +8 more
wiley +1 more source
The “Connection” Between HIV Drug Resistance and RNase H
Currently, nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) are two classes of antiretroviral agents that are approved for treatment of HIV-1 infection. Since both NRTIs and NNRTIs target the
Krista A. Delviks-Frankenberry +2 more
doaj +1 more source

