Results 141 to 150 of about 399,425 (291)

The appearance of phagocytic microglia in the postnatal brain of Niemann Pick type C mice is developmentally regulated and underscores shortfalls in fine odor discrimination

Journal of Cellular Physiology, Volume 237, Issue 12, Page 4563-4579, December 2022., 2022
Abstract The loss of NPC1 or NPC2 function results in cholesterol and sphingolipid dyshomeostasis that impairs developmental trajectories, predisposing the postnatal brain to the appearance of pathological signs, including progressive and stereotyped Purkinje cell loss and microgliosis.
Alessandro Rava, Piergiorgio La Rosa, Giampiero Palladino, Jessica Dragotto, Antonio Totaro, Jessica Tiberi, Sonia Canterini, Sergio Oddi, Maria Teresa Fiorenza   +8 more
wiley   +1 more source

Studies on the Reverse Transcriptase of RNA Tumor Viruses. Structural Relatedness of Two Subunits of Avian RNA Tumor Viruses

, 1974
Wade Gibson, Inder M. Verma
openalex   +1 more source

Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. [PDF]

, 1988
Amnon Hizi, Carolyn McGill, S H Hughes
openalex   +1 more source

Mechanism of Action of the Endonuclease Associated with the αβ and ββ Forms of Avian RNA Tumor Virus Reverse Transcriptase [PDF]

, 1983
Jonathan Leis, Geoffrey M. Duyk, Shae Johnson, Mathew Longiaru, A M Skalka   +4 more
openalex   +1 more source

ETV2 Overexpression Promotes Efficient Differentiation of Pluripotent Stem Cells to Endothelial Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Differentiating endothelial cells (ECs) from human pluripotent stem cells (hPSCs) typically takes 2 weeks and requires parameter optimization. Overexpression of cell type‐specific transcription factors in hPSCs has shown efficient differentiation into various cell types.
Yunfeng Ding, Soniya Tamhankar, Feifan Du, Tessa Christopherson, Nate Schlueter, Jenna R. Cohen, Eric V. Shusta, Sean P. Palecek   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase.

, 1978
Jeanne C. Myers, S. Spiegelman
openalex   +1 more source

A single 66-kilodalton polypeptide processed from the human immunodeficiency virus type 2 pol polyprotein in Escherichia coli displays reverse transcriptase activity [PDF]

, 1988
S F Le Grice, R. Zehnle, Jan Mous
openalex   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Boron deficiency responses in maize (Zea mays L.) roots

Journal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert, Astrid Junker, Michael Melzer, Thomas Altmann, Nicolaus von Wirén, Gerd Patrick Bienert   +5 more
wiley   +1 more source