Results 141 to 150 of about 570,932 (356)

Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions [PDF]

, 1975
Steven R. Tronick, John Stephenson, Inder M. Verma, Stuart A. Aaronson   +3 more
openalex   +1 more source

A mutate-and-map protocol for inferring base pairs in structured RNA

, 2013
Chemical mapping is a widespread technique for structural analysis of nucleic acids in which a molecule's reactivity to different probes is quantified at single-nucleotide resolution and used to constrain structural modeling.
CS Chow, D Moazed, DH Mathews, EE Regulski, JB Lucks, JG Underwood, JP Staley, KA Wilkinson, M Kertesz, M Mandal, N Kulshina, NB Leontis, P Cordero, P Cordero, P Rocca-Serra, P Tijerina, PJ Lukavsky, R Rydzanicz, RC Spitale, RF Gesteland, S Mitra, S Washietl, S Yoon, SA Mortimer, SE Wells, SM Vasa, SW Brostoff, VD Sood, W Kladwang, W Kladwang, W Kladwang, W Kladwang, Y Rhee   +32 more
core   +1 more source

Enhanced Media Optimize Bovine Myogenesis in 2D and 3D Models for Cultivated Meat Applications

Advanced Science, EarlyView.
This study uses multiomics approaches to characterize bovine myogenesis in vitro, identifying media components that enhance myogenic progenitor cell differentiation in 2D and 3D models. Notably, the enhanced conditions promoted formation of unique cell populations and contractile muscle cells expressing mature myogenic markers.
Christine L. Trautmann, Adhideb Ghosh, Ali Kerem Kalkan, Falko Noé, Ori Bar‐Nur   +4 more
wiley   +1 more source

Inhibition by RNA of RNase H Activity Associated with Reverse Transcriptase in Rauscher Murine Leukemia Virus Cores [PDF]

, 1978
M. G. Sarngadharan, V. S. Kalyanaraman, Robert C. Gallo   +2 more
openalex   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Study on immortalization of Mongolian sheep fibroblast cells

Animal Biotechnology
This study aims to establish an immortalized fibroblast cell line from Mongolian sheep. Primary Mongolian sheep fibroblasts (SSF) were isolated using tissue explant and enzymatic digestion methods, followed by microscopic observation, growth curve ...
Bin. Liu, Shichao. Wang, Fanhua. Meng, Bei. Wu, Yanru Zhang, Junwei. Cao   +5 more
doaj   +1 more source

Chicken egg yolk stabilizes the reverse transcriptase activity in type C particles produced by cultured MOPC-315 murine myeloma cells [PDF]

, 1978
Arnona Gazit, A. Yaniv, E Eylan
openalex   +1 more source

Terminal deoxynucleotidyltransferase. Serological studies and radioimmunoassay [PDF]

, 1976
Mouse antisera against calf terminal deoxynucleotidyltransferase (terminal transferase) have been prepared. The sera have been used to characterize terminal transferase both by studying inhibition of enzyme activity and by developing a competition ...
Baltimore, David, Gottlieb, Paul D., Kung, Patrick C.   +2 more
core  

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

RNA-Dependent DNA Polymerase (Reverse Transcriptase) from Avian Myeloblastosis Virus: A Zinc Metalloenzyme [PDF]

, 1974
David S. Auld, Hajime Kawaguchi, Dennis Livingston, Bert L. Vallée   +3 more
openalex   +1 more source