Results 171 to 180 of about 399,425 (291)

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

, 1989
Katarzyna Bębenek, John Abbotts, John D. Roberts, Samuel H. Wilson, Thomas A. Kunkel   +4 more
openalex   +1 more source

Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. [PDF]

, 1992
Jayne C. Boyer, Katarzyna Bębenek, Thomas A. Kunkel   +2 more
openalex   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

ESC Heart Failure, EarlyView.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse, Johanna Tennigkeit, Nikolaos Pagonas, Philipp Hillmeister, Ivo Buschmann, Martin Czolbe, Peter Nordbeck, Joachim Schmitt, Daniel Patschan, Oliver Ritter   +9 more
wiley   +1 more source

Colloidal Polyelectrolyte Complexes from Hyaluronic Acid: Preparation and Biomedical Applications

Small, Volume 18, Issue 51, December 22, 2022., 2022
Hyaluronic acid (HA) is a very promising polysaccharide for biomedical applications. This review provides a comprehensive overview of the development of nanoparticulate systems by HA‐based polyelectrolyte complexation. The main achievements and applications for the delivery of active substances or the construction of multifunctional platforms are ...
Huu Van Le, Didier Le Cerf
wiley   +1 more source

Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens. [PDF]

mBio
Hullahalli K, Dailey KG, Acbay R, Suzuki M, Balazs GI, Waldor MK.   +5 more
europepmc   +1 more source

Human immunodeficiency virus 1 reverse transcriptase

, 1989
Hans E. Huber, John McCoy, Jas Seehra, C C Richardson   +3 more
openalex   +1 more source

A phylogenetic analysis of the genus Leuconostoc based on reverse transcriptase sequencing of 16 S rRNA [PDF]

, 1990
Antonio Martínez‐Murcia, Matthew Collins   +1 more
openalex   +1 more source

Promoted read-through and mutation against pseudouridine-CMC by an evolved reverse transcriptase. [PDF]

Commun Biol
He Z, Qiu W, Zhou H.
europepmc   +1 more source

Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis [PDF]

, 1994
Bep Klaver, Ben Berkhout
openalex   +1 more source

Engineered brain‐targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma

Exploration, EarlyView.
An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang, Yong Li, Shaoping Jiang, Yuxin Tian, Mengjie Zhang, Shuai Guo, Pengfei Wu, Jianan Li, Lin Xu, Wenpei Li, Yushu Wang, Huile Gao, Yuanyu Huang, Yuhua Weng, Shaobo Ruan   +14 more
wiley   +1 more source