Telomerase reverse transcriptase mediates bone formation for osteoporosis via activating BMP4/Smad1 pathway. [PDF]
Ma J +9 more
europepmc +1 more source
Essential roles of telomerase reverse transcriptase hTERT in cancer stemness and metastasis
Ricarda Hannen, J. Bartsch
semanticscholar +1 more source
Discovery of the reverse transcriptase
1995 is the 20th anniversity of the award of the Nobel Prize in Physiology or Medicine to David Baltimore and Howard Temin for the discovery of the reverse transcriptase.
Baltimore, David
core
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Enhancing the efficiency of nuclease-based prime editing in rice with the Tf1 reverse transcriptase. [PDF]
Ma G +7 more
europepmc +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
The impact of the recent HIV non-nucleoside reverse transcriptase inhibitors and nucleoside reverse transcriptase inhibitors-based regimens on metabolic health outcomes: A narrative review. [PDF]
Sedibe A +3 more
europepmc +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Harnessing machine learning models to repurpose drugs targeting HIV-1 integrase, protease, and reverse transcriptase. [PDF]
Chirila CB, Crisan L.
europepmc +1 more source
Background Activity of Reverse Transcriptases [PDF]
Angelica V. Timofeeva +1 more
openaire +3 more sources

