Results 211 to 220 of about 1,799,385 (351)

Approaches to repurposing reverse transcriptase antivirals in cancer. [PDF]

Br J Clin Pharmacol
Head R, Islam S, Martin JH.
europepmc   +1 more source

Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction

Journal of Clinical Microbiology, 1992
R. Lanciotti, C. Calisher, D. Gubler, G. J. Chang, A. Vorndam   +4 more
semanticscholar   +1 more source

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

Reverse transcriptase inhibitors enable the generation of fertile spermatids from fetal mouse testes in vitro. [PDF]

Commun Biol
Nishida M, Ono-Sunagare Y, Kato S, Ishikawa-Yamauchi Y, Matsumura T, Komeya M, Matoba S, Inoue K, Ogonuki N, Ogura A, Ogawa T, Sato T.   +11 more
europepmc   +1 more source

Synthetic evolutionary origin of a proofreading reverse transcriptase

Science, 2016
Jared W. Ellefson, J. Gollihar, Raghav Shroff, H. Shivram, V. Iyer, A. Ellington   +5 more
semanticscholar   +1 more source

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source

Structural basis of antiphage defence by an ATPase-associated reverse transcriptase. [PDF]

Nat Commun
George JT, Burman N, Wilkinson RA, de Silva S, McKelvey-Pham Q, Buyukyoruk M, Dale A, Landman H, Graham AB, DeLuca SZ, Wiedenheft B.   +10 more
europepmc   +1 more source

Matching TGF‐β1 Activation With Stress‐Responsive Charge‐Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis

Exploration, EarlyView.
Based on the interaction between the weakly cross‐linked disulfide bonds that break under stress and charge‐reversal messenger molecules, we herein achieved nanoparticle charge reversal under stress and constructed a stress‐responsive charge‐reversal hydrogel microsphere system using microfluidic technology.
Feng Lin, Yiwen Xu, Lei Xiang, Yueliang Zhu, Yihan Li, Yaping Zhuang, Zengjie Zhang, Jiayu Chen, Heemin Kang, Ning Zhang, Xiaohua Yu, Wenguo Cui   +11 more
wiley   +1 more source

Structural biology of HIV-1 reverse transcriptase allosteric inhibitors for drug design. [PDF]

Acta Pharm Sin B
Zhou Z, Sun Y, Feng D, Wang Z, Zhao F, Gao S, Zhan P, Kang D, Liu X.   +8 more
europepmc   +1 more source

Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression.

Journal of Clinical Investigation, 2016
Ekta Khattar, Pavanish Kumar, Chia-yi Liu, S. C. Akıncılar, Anandhkumar Raju, Manikandan Lakshmanan, J. Maury, Yu Qiang, Shang Li, E. Tan, K. Hui, Minghao Shi, Joey Loh, V. Tergaonkar   +13 more
semanticscholar   +1 more source