Results 211 to 220 of about 965,759 (306)

A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease. [PDF]

Exp Mol Med
Lee Y, Nam H, Lee JW, Ko YJ, Kim EJ, Ha S, Kim N, Koo JW, Son T, Kim S, Yu SW.   +10 more
europepmc   +1 more source

Dosing HIV integrase inhibitors with enzyme inducers: Convenience vs. control?

British Journal of Clinical Pharmacology, EarlyView.
Catia Marzolini, Saye Khoo
wiley   +1 more source

Enhancing the efficiency of nuclease-based prime editing in rice with the Tf1 reverse transcriptase. [PDF]

aBIOTECH
Ma G, Xu H, Zhang S, Li X, Liu J, Xie J, Yan F, Zhou H.   +7 more
europepmc   +1 more source

The impact of the recent HIV non-nucleoside reverse transcriptase inhibitors and nucleoside reverse transcriptase inhibitors-based regimens on metabolic health outcomes: A narrative review. [PDF]

Biochem Biophys Rep
Sedibe A, Sibiya N, Nyakudya T, Gamede M.   +3 more
europepmc   +1 more source

Telomerase reverse transcriptase mediates bone formation for osteoporosis via activating BMP4/Smad1 pathway. [PDF]

J Orthop Translat
Ma J, Yuan X, Xiao Y, Wang H, Hong Y, Zhang Y, Chen Y, Zheng H, Li J, Li B.   +9 more
europepmc   +1 more source

Improved Prediction of Colon Cancer Recurrence Using the ColoNode mRNA Test: A 5‐Year Survival Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Twenty‐five percent of colon cancer patients having curative surgery will recur. Most of them will die from distant metastasis partly due to shortcomings of routine histopathological analysis, that is, undetected tumor cells in the regional lymph node field.
Basel Sitohy, Gudrun Lindmark, Anne Israelsson, Lina Olsson, Tamer Roshdy, Joel Blomqvist, Sara Kero, Mattias Söderholm, Annamaria Turi, Thorbjörn Sakari, Michiel Dooper, George Dafnis, Pehr Forsberg, Susanne Skovsted, Maria Walldén, Chih‐Han Kung, Martin Rutegård, Johanna Nordmyr, Måns Muhrbeck, Sten Hammarström, Marie‐Louise Hammarström   +20 more
wiley   +1 more source

Harnessing machine learning models to repurpose drugs targeting HIV-1 integrase, protease, and reverse transcriptase. [PDF]

Sci Rep
Chirila CB, Crisan L.
europepmc   +1 more source

The womb as the cradle of longevity: Perinatal origins of biological aging

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and ...
Sevim Ozge Ozdemir, Ebru Davutoglu
wiley   +1 more source

Nucleoside-Analog Reverse-Transcriptase Inhibitors (NRTIs) Against Multiple Sclerosis: Comprehensive Review on a Possible Novel Therapeutic Approach. [PDF]

Neurol Int
Martinisi A, Paganetti P.
europepmc   +1 more source

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source