Results 201 to 210 of about 965,759 (306)

Human telomerase reverse transcriptase supports respiratory syncytial virus replication. [PDF]

Commun Biol
Huynh H, Wu CT, Kahn JS.
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Study of Telomere Length Kinetics and Telomerase Reverse Transcriptase Gene Polymorphism in Children Undergoing Allogeneic Haematopoietic Stem Cell Transplantation. [PDF]

Genes (Basel)
Häusler K, Dratwa-Kuzmin M, Ussowicz M, Rybka B, Ryczan-Krawczyk R, Kalwak K, Bogunia-Kubik K.   +6 more
europepmc   +1 more source

Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications

Food Chemistry International, EarlyView.
Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan, Jumanah Reda Kurdi, Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi   +4 more
wiley   +1 more source

Enhanced strand transfer and mismatch extension by HIV-1C reverse transcriptase promote sequence motif duplication. [PDF]

J Virol
Panchapakesan A, Joshi AP, Amanullah A, Pargain N, Mehta K, Shanmugam M, Singh J, Saini C, Nala N, Ramagopal UA, Ranga U.   +10 more
europepmc   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

1,4-Dihydroxy-1,8-napthyridinone (DHN) analogs as HIV-1 reverse transcriptase-associated RNase H inhibitors. [PDF]

Bioorg Chem
Shahari MSB, Offei S, Zhang H, Prahlad J, Mahoney JP, Kirby KA, Sarafianos SG, Wang Z.   +7 more
europepmc   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Human Telomerase Reverse-Transcriptase Promoter-Controlled and Herpes Simplex Virus Thymidine Kinase-Armed Adenoviruses for Renal Cell Carcinoma Treatment [Retraction]. [PDF]

Onco Targets Ther
europepmc   +1 more source

HIV-1 genetic diversity and reverse transcriptase resistance mutations in Benin before dolutegravir era, West Africa. [PDF]

PLoS One
Tchiakpe E, Keke RK, Recordon-Pinson P, Diouara AAM, Andreola ML, Bachabi M, Afangnihoun A, Gbaguidi E, Osawe S, Issiaka Maiga A, Diop-Ndiaye H, Touré-Kane C, Yessoufou A.   +12 more
europepmc   +1 more source