Results 221 to 230 of about 1,799,385 (351)

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Synthesis, in vitro anti-HIV-1 reverse transcriptase evaluation, molecular modelling, DFT analysis and acute oral toxicity assessment of benzotriazole derivatives. [PDF]

Sci Rep
Maiti NJ, Ganguly S, Choowongkomon K, Seetaha S, Saehlee S, Aiebchun T, Ghosh R, Khan MA, Debnath B, Nath R, Ashique S, Singh NK, Ansari MY, Tariq M, Niazi P.   +14 more
europepmc   +1 more source

Development of a Real-Time Reverse Transcriptase PCR Assay for Type A Influenza Virus and the Avian H5 and H7 Hemagglutinin Subtypes

Journal of Clinical Microbiology, 2002
E. Spackman, D. Senne, T. J. Myers, L. L. Bulaga, L. Garber, M. Perdue, K. Lohman, L. Daum, D. Suarez   +8 more
semanticscholar   +1 more source

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah, Lessandra Y. S. Chee, Jie Su, Brian O'Sullivan, Christopher M. K. L. Yao, Enrique Sanz‐Garcia, Stephen M. Smith, Ilan Weinreb, Scott Bratman, B. C. John Cho, Ezra Hahn, Andrew Hope, Ali Hosni, John Kim, Andrew McPartlin, Nauman Malik, Chiaojung Jillian Tsai, John de Almeida, Anna Spreafico, Li Tong, Shao Hui Huang, John N Waldron   +21 more
wiley   +1 more source

Allophycocyanin inhibits HIV-1 gp120 and reverse transcriptase through enthalpy-driven binding and antioxidative protection: integrative computational and experimental insights. [PDF]

Sci Rep
Dubey A, Kumar M, Tufail A, Anand K, Sengupta S.   +4 more
europepmc   +1 more source

Lyophilised Reverse Transcriptase and Polymerase for Point-of-Care Diagnostics of SARS-CoV-2. [PDF]

Microb Biotechnol
Mutter N, Posch B, Gillitschka Y, Kataeva N, Michalek B, Lager D, Staniszewski F, Schilder A, Osinkina L, Westenthanner M, Stehr J, Buersgens F, Peham JR.   +12 more
europepmc   +1 more source

Optimisation of peptides targeting reverse transcriptase HIV-1 using QSAR, machine learning, and computational approaches. [PDF]

Front Pharmacol
Mahendra FR, Prakoso I, Marzelino A, Rizqy Fadhillah M, Syukriyansyah, Hasibuan MMA, Suparningtyas JF, Kristiadi M, Setiawan AG, Rahman FI, Sari AN, Raysendria NR, Kurniawan I, Arozal W, Kusmardi K.   +14 more
europepmc   +1 more source

Clinical Performance of the Loop-Mediated Isothermal Amplification Method Compared With Reverse Transcriptase Polymerase Chain Reaction for COVID-19 Diagnosis in Indonesia and the Philippines. [PDF]

Cureus
Mizushima R, Suriapranata IM, Geraldino N, Kurniasih TS, Andriani F, Cucunawangsih, Wijaya RS, Lugito NP, Hernandez-Diwa M, Ang MA, Ozoa GM, Uy TCF, Tabunar SM, Germar MJ, Urbiztondo-Benedicto MT, Saito S, Yamamoto K, Sakaguchi M, Hosaka N, Koyano S, Siburian MD, Umano-Urbiztondo MR, Kobayashi T, Miura T, Ohmagari N.   +24 more
europepmc   +1 more source

Protein-primed homopolymer synthesis by an antiviral reverse transcriptase. [PDF]

Nature
Tang S, Žedaveinytė R, Burman N, Pandey S, Ramirez JL, Kulber LM, Wiegand T, Wilkinson RA, Ma Y, Zhang DJ, Lampe GD, Berisa M, Jovanovic M, Wiedenheft B, Sternberg SH.   +14 more
europepmc   +1 more source

The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma

International Journal of Cancer, EarlyView.
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Lotteke J. Y. M. Ziel‐Swier, Karolina Rassek, Yichen Liu, Annika Seitz, Jasper Koerts, Debora de Jong, Bea Rutgers, Anastasiia Kompaniiets, Julia Przybył, Martine E. D. Chamuleau, Anke van den Berg, Agnieszka Dzikiewicz‐Krawczyk, Joost Kluiver   +12 more
wiley   +1 more source