Results 251 to 260 of about 382,156 (284)
Correction to "SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression". [PDF]
Mol Oncoleuropepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Retroviral reverse transcriptases
Cellular and Molecular Life Sciences, 2010Reverse transcription is a critical step in the life cycle of all retroviruses and related retrotransposons. This complex process is performed exclusively by the retroviral reverse transcriptase (RT) enzyme that converts the viral single-stranded RNA into integration-competent double-stranded DNA.
Alon, Herschhorn, Amnon, Hizi
openaire +2 more sources
Biochemical Education, 1995
Abstract The reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) converts the single-stranded (+) viral RNA genome into double¬ stranded proviral DNA prior to its integration into the host genomic DNA. The HIV-1 RT has therefore been the target for anti-viral drug design (1). The cloning of the RT in biologically
W A Beard, S H Wilson
openaire +2 more sources
Abstract The reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) converts the single-stranded (+) viral RNA genome into double¬ stranded proviral DNA prior to its integration into the host genomic DNA. The HIV-1 RT has therefore been the target for anti-viral drug design (1). The cloning of the RT in biologically
W A Beard, S H Wilson
openaire +2 more sources
Biochemical and Biophysical Research Communications, 1974
Summary Purified DNA polymerase (“reverse transcriptase”) from avian myeloblastosis virus was analyzed for zinc by atomic absorption spectroscopy. Tightly bound zinc was present in a stoichiometry approximating 1 gm atom/mole of enzyme. Inhibition by the chelating agent, ortho -phenanthroline, and lack of inhibition by its non-chelating analog ...
B J, Poiesz, N, Battula, L A, Loeb
openaire +2 more sources
Summary Purified DNA polymerase (“reverse transcriptase”) from avian myeloblastosis virus was analyzed for zinc by atomic absorption spectroscopy. Tightly bound zinc was present in a stoichiometry approximating 1 gm atom/mole of enzyme. Inhibition by the chelating agent, ortho -phenanthroline, and lack of inhibition by its non-chelating analog ...
B J, Poiesz, N, Battula, L A, Loeb
openaire +2 more sources
Reverse transcriptase in bacteria
Molecular Microbiology, 1989SummaryReverse transcriptase, discovered in 1970 in retroviruses, has until recently been found only in eukaryotic organisms. Recently it was shown to occur in two groups of bacteria: myxobacteria and Escherichia coli. The gene for reverse transcriptase is part of a chromosomal genetic element that codes for the production of a branched DNA‐RNA ...
D, Lim, W K, Maas
openaire +2 more sources
Bacterial reverse transcriptase and msDNA
Virus Genes, 1995Retrons are a new class of genetic elements found in the chromosome of a large number of different bacteria. These elements code for a reverse transcriptase (RT) that is structurally similar to the polymerases of retroviruses. The retron associated RT is responsible for the production of an unusual extrachromosomal satellite DNA, known as multicopy ...
S A, Rice, B C, Lampson
openaire +2 more sources
New Reverse Transcriptase Inhibitors
1999Reverse transcriptase inhibitors used in the treatment of HIV-1 infection include the nucleoside analogues zidovudine, didanosine, zalcitabine, lamivudine and stavudine. More recently a number of other classes of reverse transcriptase inhibitors have been discovered, and are in various phases of clinical trial. This chapter will focus on the nucleoside
openaire +2 more sources