Results 251 to 260 of about 399,425 (291)

Detection of estrogen receptor messenger ribonucleic acid in human oocytes and cumulus-oocyte complexes using reverse transcriptase-polymerase chain reaction

, 1993
Tsung-Chieh Jackson Wu, Lai Wang, Yu‐Jui Yvonne Wan   +2 more
openalex   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source

EPSPS target site mechanisms confer glyphosate resistance in Arctotheca calendula

Pest Management Science, EarlyView.
This investigation revealed that the EPSPS gene mutation resulting in Pro‐106‐Ser substitution and EPSPS overexpression endow resistance to glyphosate in the capeweed population. Abstract BACKGROUND The first case of glyphosate resistance was reported in a capeweed population from Western Australia in our previous study. This current study investigates
Norazua Zakaria, Heping Han, Yaseen Khalil, Michael Ashworth, Qin Yu, Ken C Flower   +5 more
wiley   +1 more source

Research Note: Development of a reverse transcriptase recombinase-aided amplification method for detection of Parrot Borna Virus 4. [PDF]

Poult Sci
Bai Y, Dong G, Zhang P, Dong M, Rao J, Wang Q, Shao R, Liu R, Feng K, Xie Q, Zhang X.   +10 more
europepmc   +1 more source

An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Med Chem
Fabbrizi E, Chernyshov VV, Fiorentino F, Sbardella G, Ragno R, Nawrozkij M, Ivanov R, Rotili D, Mai A.   +8 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Nucleoside Reverse Transcriptase Inhibitors Are the Major Class of HIV Antiretroviral Therapeutics That Induce Neuropathic Pain in Mice. [PDF]

Int J Mol Sci
Bush K, Wairkar Y, Tang SJ.
europepmc   +1 more source

Systemic Brain Delivery of Oligonucleotide Therapeutics Enhanced by Protein Corona‐Assisted DNA Cubes

Small Methods, EarlyView.
In vivo, screening of DNA nanostructures yields a cube‐shaped structure (D‐Cb) as a protein corona‐assisted platform for brain delivery of oligonucleotide therapeutics. D‐Cb effectively delivers polo‐like kinase 1 (PLK‐1) antisense oligonucleotides (ASO) to treat glioblastoma in an orthotopic mouse model, demonstrating its potential as a carrier for ...
Kyoung‐Ran Kim, Ji Hee Kang, Hien Bao Dieu Thai, Ji Hyun Back, Chengde Mao, Ji Eun Lee, Young Tag Ko, Dae‐Ro Ahn   +7 more
wiley   +1 more source

Liver Damage During Treatment with Reverse-Transcriptase Inhibitors in HIV Patients. [PDF]

Curr Health Sci J
Lungu GN, Diaconescu GI, Dumitrescu F, Docea OO, Mitrut R, Giubelan L, Zlatian O, Mitrut P.   +7 more
europepmc   +1 more source

Rapid Amplification and Detection of Single‐Stranded Nucleic Acids for Point‐of‐Care Diagnosis

Small Methods, EarlyView.
A rapid, point‐of‐care nucleic acid test can greatly benefit healthcare system by providing timely diagnosis for effective treatment and patient management, as well as supporting diseases surveillance for emerging pandemic diseases. Recent advancements in nucleic acids technology have led to rapid assays for single‐stranded nucleic acids that can be ...
Jinglin Fu, Qiaochu Zhang, Shiming Liu, Derek Puyat, Akshay Shah, Alireza Ebrahimimojarad, Sung Won Oh   +6 more
wiley   +1 more source