Results 251 to 260 of about 1,799,385 (351)

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

Science, 2014
B. Fowler, B. Gelfand, Younghee Kim, N. Kerur, Valeria Tarallo, Yoshio Hirano, Shoba Amarnath, D. Fowler, M. Radwan, M. Young, K. Pittman, P. Kubes, H. Agarwal, K. Parang, D. Hinton, A. Bastos-Carvalho, Shengjian Li, T. Yasuma, Takeshi Mizutani, Reo Yasuma, Charles B. Wright, J. Ambati   +21 more
semanticscholar   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Characterization of LTR Retrotransposon Reverse Transcriptase in <i>Tamarix chinensis</i> L. and Activity Analysis Under Salt and Alkali Stresses. [PDF]

Genes (Basel)
Wang L, Li B, Wang Y, Wang S, Zhang M, Li M, Zheng T, Wang H.   +7 more
europepmc   +1 more source

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

Journal of Virology, 1995
L. Mansky, H. Temin
semanticscholar   +1 more source

Apple scar skin viroid causes dapple and scar skin apple diseases by disrupting phenylpropanoid‐mediated metabolic pathways

New Plant Protection, EarlyView.
Dapple apple and scar skin apple diseases are closely associated with suppression of anthocyanin biosynthesis and enhancement of suberin biosynthesis. Apple scar skin viroid (ASSVd) infection represses anthocyanin biosynthesis in apple callus. Abstract Apple scar skin viroid (ASSVd) causes dapple and scar skin apple diseases, posing serious threats to ...
Lingzhu He, Huiyuan Xu, Tao Zhou, Naoi Takashi, Sano Teruo, Guojun Hu, Jipeng Xie, Xiuling Yang, Shifang Li, Zhixiang Zhang   +9 more
wiley   +1 more source

Effectiveness and safety of two-drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE-2 study. [PDF]

HIV Med
Mussini C, Henegar C, Assoumou L, de Wit S, Johnson M, Quiros-Roldan E, Kenyon C, Deschanvres C, Zucman D, Post F, Movahedi R, Comi L, Fox J, Liegeon G, Martin C, Edwards J, Tiecco G, Delforge M, Ragone L, Jones B, van Wyk J, Aboud M, Fletcher C, Pozniak A, Vannappagari V.   +24 more
europepmc   +1 more source

The Expanding Role of Companion Diagnostics in Infectious Diseases: Lessons From Abacavir and Human Immunodeficiency Virus Care

iLABMED, EarlyView.
Yi‐Wei Tang, Eric von Hofe
wiley   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, EarlyView.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

Evaluation of immunohistochemical and gene expression of Janus kinase 1 and Janus kinase 3 in the skin of different clinical types of mycosis fungoides patients - Part II: reverse transcriptase-polymerase chain reaction. [PDF]

An Bras Dermatol
El-Amawy HS, Mohamed Ali BM, Salem ML, Elgarhy L.   +3 more
europepmc   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source