The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors. [PDF]
Viruses, 2023 Fernandes LDR +5 more
europepmc +1 more source
Prevalence of etravirine (TMC-125) resistance mutations in HIV-infected patients with prior experience of non-nucleoside reverse transcriptase inhibitors [PDF]
, 2007 Eva Poveda +6 more
openalex +1 more source
Advanced Science, EarlyView.Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang +12 more
wiley +1 more source
Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs). [PDF]
Viruses, 2023 Vanangamudi M +3 more
europepmc +1 more source
Disrupting endogenous retroelements with a reverse transcriptase inhibitor alleviates DSS-induced colitis in mice [PDF]
, 2023 Yifan Niu +8 more
openalex +1 more source
A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time
Advanced Science, EarlyView.This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li +15 more
wiley +1 more source
RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication
Advanced Science, EarlyView.Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song +11 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Kasmera, 2010 A prospective study was carried out to determine the effect of antiretroviral therapy on the lipid profile in a population of 50 patients with AIDS who received their first antiretroviral drug treatment in the HIV-AIDS clinic at the Maracaibo University ...
Isabel Soto +2 more
doaj
Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise. [PDF]
Protein Sci, 2023 Hollander K +9 more
europepmc +1 more source