Results 161 to 170 of about 1,271,708 (300)

Inhibition of long interspersed nuclear element-1 by nucleoside reverse transcriptase inhibitors attenuates vascular calcification. [PDF]

Signal Transduct Target Ther
Ma J, He D, Zhang M, Zhou Z, Cheng J, Huang A, Lian Y, Shi Y, Xie C, Guan Z, Zhang Z, Xie C, Zhang T, Huang H.   +13 more
europepmc   +1 more source

Improved Prediction of Colon Cancer Recurrence Using the ColoNode mRNA Test: A 5‐Year Survival Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Twenty‐five percent of colon cancer patients having curative surgery will recur. Most of them will die from distant metastasis partly due to shortcomings of routine histopathological analysis, that is, undetected tumor cells in the regional lymph node field.
Basel Sitohy, Gudrun Lindmark, Anne Israelsson, Lina Olsson, Tamer Roshdy, Joel Blomqvist, Sara Kero, Mattias Söderholm, Annamaria Turi, Thorbjörn Sakari, Michiel Dooper, George Dafnis, Pehr Forsberg, Susanne Skovsted, Maria Walldén, Chih‐Han Kung, Martin Rutegård, Johanna Nordmyr, Måns Muhrbeck, Sten Hammarström, Marie‐Louise Hammarström   +20 more
wiley   +1 more source

Reverse transcriptase inhibitors in Aicardi-Goutières syndrome: A crossover clinical trial. [PDF]

Dev Med Child Neurol
Crow YJ, Briggs TA, Eleftheriou D, Parida A, Battison C, Giddings A, Kennel T, Parker RA, AGS‐RTIs Study Group.   +8 more
europepmc   +1 more source

The Influence of Nucleoside Reverse Transcriptase Inhibitors on Mitochondrial Activity, Lipid Content, and Fatty-Acid-Binding Protein Levels in Microglial HMC3 Cells. [PDF]

Pharmaceuticals (Basel), 2023
Lipke K, Kubis-Kubiak A, Piwowar A.
europepmc   +1 more source

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, EarlyView.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

In vitro comparison of the susceptibilities of the same drug resistance mutations to reverse-transcriptase inhibitors of subtype B and CRF01_AE HIV-1 strains. [PDF]

Sci Rep
Li H, Shen K, Han J, Liu Y, Zhang L, Liu X, Jia L, Zhang B, Wang X, Li J, Dai E, Yan H, Li L.   +12 more
europepmc   +1 more source

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors. [PDF]

Commun Chem, 2023
Jiang X, Huang B, Rumrill S, Pople D, Zalloum WA, Kang D, Zhao F, Ji X, Gao Z, Hu L, Wang Z, Xie M, De Clercq E, Ruiz FX, Arnold E, Pannecouque C, Liu X, Zhan P.   +17 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Design, Synthesis, and Biological Activity of Amine-Type Cyclopentanepyridinone Derivatives as HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors. [PDF]

ACS Omega
Castro-Perea NV, Rodríguez-Vega G, Abarca-Magaña JC, Ruiz-Rivera MB, Medina-Franco JL, Huerta L, Chávez D.   +6 more
europepmc   +1 more source

Erratum: Author correction to 'Approved HIV reverse transcriptase inhibitors in the past decade' [Acta Pharmaceutica Sinica B 12 (2022) 1567-1590]. [PDF]

Acta Pharm Sin B, 2023
Li G, Wang Y, De Clercq E.
europepmc   +1 more source