Results 201 to 210 of about 125,916 (291)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Indolylarylsulfones Bearing Natural and Unnatural Amino Acids. Discovery of Potent Inhibitors of HIV-1 Non-Nucleoside Wild Type and Resistant Mutant Strains Reverse Transcriptase and Coxsackie B4 Virus

, 2009
Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri   +14 more
openalex   +1 more source

Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling [PDF]

, 2009
Romulus Breban, Sonia Napravnik, James S. Kahn, Sally Blower   +3 more
openalex   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Nucleoside Reverse Transcriptase Inhibitors Are the Major Class of HIV Antiretroviral Therapeutics That Induce Neuropathic Pain in Mice. [PDF]

Int J Mol Sci
Bush K, Wairkar Y, Tang SJ.
europepmc   +1 more source

Nucleoside and non-nucleoside reverse transcriptase inhibitor drugs (NRTIs and NNRTIs) are capable of binding Chandipura virus polymerase protein (L) and inhibit virus replication

Dibyakanti Mandal, Deeksha Pandey, Debi P. Sarkar, Manish Kumar   +3 more
openalex   +2 more sources

Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection

, 2015
Thulani H. Senanayake, Santhi Gorantla, Edward Makarov, Yaman Lu, Galya Warren, С. В. Виноградов   +5 more
openalex   +1 more source

Clinical benefits of novel non-nucleoside reverse transcriptase inhibitors: A prospective cohort study. [PDF]

Immun Inflamm Dis
Ma S, Xie X, Fu Y, Gan L, Yang X, Kong L, Li J, Long H.   +7 more
europepmc   +1 more source

A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitors [PDF]

, 1997
Chaofu Shi, John W. Mellors
openalex   +1 more source

Association between the CYP2B6 polymorphisms and nonnucleoside reverse transcriptase inhibitors drug-induced liver injury: a systematic review and meta-analysis. [PDF]

Sci Rep
Chanhom N, Sonjan J, Inchai J, Udomsinprasert W, Chaikledkaew U, Suvichapanich S, Mahasirimongkol S, Jittikoon J.   +7 more
europepmc   +1 more source