Results 211 to 220 of about 1,271,708 (300)

Brief Report: Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors and the Risk of Cancer Among People With HIV. [PDF]

J Acquir Immune Defic Syndr
Coburn SB, Pimentel N, Leyden W, Kitahata MM, Moore RD, Althoff KN, Gill MJ, Lang R, Horberg MA, D'Souza G, Hussain SK, Dubrow R, Novak RM, Rabkin CS, Park LS, Sterling TR, Neugebauer RS, Silverberg MJ, North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS.   +18 more
europepmc   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection. [PDF]

Proc Natl Acad Sci U S A
Hullahalli K, Dailey KG, Hasegawa Y, Johnson WE, Waldor MK.   +4 more
europepmc   +1 more source

Enhanced fish detection sensitivity in aquatic systems using environmental RNA

Methods in Ecology and Evolution, EarlyView.
Abstract Environmental RNA (eRNA) can potentially augment the biological monitoring ability of the established environmental DNA (eDNA) application in conservation. Despite faster degradation, environmental RNA could offer unique advantages: it may help reduce the legacy signal compared to eDNA, provide insights into physiological status through gene ...
Ana Ramón‐Laca, Ramón Gallego, Carmen Duque, José L. J. Ledesma, Ignacio Doadrio, Kim M. Parsons, Krista M. Nichols, Samantha Engster, Abigail Wells, Ana Riesgo   +9 more
wiley   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Comprehensive Chemical Analysis of the Methyl 3-Nitrogen-2,3-Dideoxysaccharides Derivatives with d-<i>ribo</i>-Configuration: Synthesis, Reactivity of HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Phys Chem B
Dąbrowska AM, Kaźmierkiewicz R, Barabaś-Lepak AM, Biedulska M, Chylewska A.   +4 more
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Ezh2 Inhibits the Differentiation of Short‐Lived Effector CD8+ T Cells and Promotes T Cell‐Dependent Antitumor Immunity

Cancer Science, EarlyView.
The antitumor immune response is attenuated in T cell‐specific Ezh2 knockout mice. ABSTRACT Appropriate regulation of the differentiation balance between effector CD8+ T cells and memory CD8+ T cells is crucial for an appropriate immune response. We previously reported that the tumor suppressor menin suppresses the differentiation of CD8+ T cells into ...
Kenji Takagi, Junpei Suzuki, Yuko Matsuoka, Makoto Kuwahara, Taro Oshikiri, Masakatsu Yamashita   +5 more
wiley   +1 more source

Profiling the Interaction between Human Serum Albumin and Clinically Relevant HIV Reverse Transcriptase Inhibitors. [PDF]

Viruses
Costa-Tuna A, Chaves OA, Almeida ZL, Cunha RS, Pina J, Serpa C.   +5 more
europepmc   +1 more source