Results 281 to 290 of about 399,014 (392)

Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral Agent [PDF]

, 2001
Giuseppe Campiani, Francesca Aiello, Monica Fabbrini, Elena Morelli, Anna Ramunno, Silvia Armaroli, Vito Nacci, Antonio Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, Laura Ventura, Barbara Bongiovanni, M Capozzi, Francesca Bolacchi, Stefano Marini, Massimo Coletta, Giovanna Guiso, Silvio Caccia   +20 more
openalex   +1 more source

Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as common pathway

AIDS (London), 1998
K. Brinkman, H. T. ter Hofstede, D. Burger, J. Smeitink, P. Koopmans   +4 more
semanticscholar   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Convergent Evolution of Reverse Transcriptase (RT) Genes of Human Immunodeficiency Virus Type 1 Subtypes E and B following Nucleoside Analogue RT Inhibitor Therapies

, 2000
Hironori Sato, Yasuhiro Tomita, Kayo Shibamura, Teiichiro Shiino, Tuyoshi Miyakuni, Yutaka Takebe   +5 more
openalex   +1 more source

Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine

Antimicrobial Agents and Chemotherapy, 2013
Hong-tao Xu, S. Colby-Germinario, Eugene Asahchop, Maureen Oliveira, M. McCallum, Susan M. Schader, Yingshan Han, Y. Quan, S. Sarafianos, M. Wainberg   +9 more
semanticscholar   +1 more source

A survey of resistance mutations to reverse transcriptase inhibitors (RTIs) among HIV-1 patients in northeast of Iran. [PDF]

Mol Biol Res Commun
Mazaheri Z, Tahaghoghi-Hajghorbani S, Baesi K, Ghazvini K, Amel-Jamehdar S, Youssefi M.   +5 more
europepmc   +1 more source

Rapid Amplification and Detection of Single‐Stranded Nucleic Acids for Point‐of‐Care Diagnosis

Small Methods, EarlyView.
A rapid, point‐of‐care nucleic acid test can greatly benefit healthcare system by providing timely diagnosis for effective treatment and patient management, as well as supporting diseases surveillance for emerging pandemic diseases. Recent advancements in nucleic acids technology have led to rapid assays for single‐stranded nucleic acids that can be ...
Jinglin Fu, Qiaochu Zhang, Shiming Liu, Derek Puyat, Akshay Shah, Alireza Ebrahimimojarad, Sung Won Oh   +6 more
wiley   +1 more source

Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration

The Lancet, 2008
C. Sabin, S. Worm, R. Weber, P. Reiss, W. El-Sadr, F. Dabis, S. De Wit, M. Law, A. d’Arminio Monforte, N. Friis‐Møller, O. Kirk, C. Pradier, I. Weller, A. Phillips, J. Lundgren   +14 more
semanticscholar   +1 more source

Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluation. [PDF]

Int J Mol Sci
Zhuo Z, Wang Z, Jing L, Zhang T, Ge A, Zhou Z, Liu Y, Li X, De Clercq E, Pannecouque C, Zhan P, Liu X, Kang D.   +12 more
europepmc   +1 more source

Synthesis and molecular docking studies of quinoline derivatives as HIV non-nucleoside reverse transcriptase inhibitors. [PDF]

Turk J Chem, 2020
Bhardwaj N, Choudhary D, Pathania A, Baranwal S, Kumar P.   +4 more
europepmc   +1 more source