Results 221 to 230 of about 273,066 (341)

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Validation of Endogenous Control Genes by Real-Time Quantitative Reverse Transcriptase Polymerase Chain Reaction for Acute Leukemia Gene Expression Studies. [PDF]

Genes (Basel)
Pessoa FMCP, Viana VBJ, de Oliveira MB, Nogueira BMD, Ribeiro RM, Oliveira DS, Lopes GS, Vieira RPG, de Moraes Filho MO, de Moraes MEA, Khayat AS, Moreira FC, Moreira-Nunes CA.   +12 more
europepmc   +1 more source

Diagnostic Performance of CT and Reverse Transcriptase Polymerase Chain Reaction for Coronavirus Disease 2019: A Meta-Analysis. [PDF]

Radiology, 2020
Kim H, Hong H, Yoon SH.
europepmc   +1 more source

Epidemiology, Outcomes, and Associated Factors of Coronavirus Disease 2019 (COVID-19) Reverse Transcriptase Polymerase Chain Reaction-Confirmed Cases in the San Pedro Sula Metropolitan Area, Honduras. [PDF]

Clin Infect Dis, 2021
Zuniga-Moya JC, Norwood DA, Romero Reyes LE, Barrueto Saavedra E, Diaz R, Fajardo WC, Pineda A, Torres D, Barahona R, Leiva SO, Hernandez PX, Silva H, Leiva CR, Estrada L, Barahona-Campos A, Gordon A.   +15 more
europepmc   +1 more source

Evaluation of the reverse transcriptase/polymerase chain reaction for carcinoembryonic antigen for the detection of breast cancer dissemination in bone marrow and peripheral blood

, 1999
Xiao Yan Zhong, Sepp Kaul, John A. Thompson, Astrid Eichler, G. Bastert   +4 more
openalex   +2 more sources

BMP‐Dependent Modulation of ROS Generation and Scavenging Controls Interdigital Cell Death

Development, Growth &Differentiation, EarlyView.
BMP signaling regulates ROS generation and scavenging to control interdigital cell death in the developing chicken limb, highlighting a balance between oxidative stress and tissue regression. ABSTRACT Programmed cell death during embryonic development plays a vital role in shaping limb morphology in amniotes.
Satomi F. Ono, Rikito Furukawa, Ingrid Rosenburg Cordeiro, Kaori Kabashima, Kyohei Yoshida, Taiki Hatano, Koki Hayafune, Makoto Kashima, Akiha Kagehira, Reiko Yu, Toru Kawanishi, Mikiko Tanaka   +11 more
wiley   +1 more source

Direct detection of canine picornavirus complete coding sequence in wastewater using long-range reverse-transcriptase polymerase chain reaction and long-read sequencing. [PDF]

Infect Genet Evol
Faleye TOC, Driver EM, Wright JM, Halden RU, Varsani A, Scotch M.   +5 more
europepmc   +1 more source

Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro [PDF]

, 1998
R. Jung, William Krüger, Stefan B. Hosch, Michael Holweg, Nicolaus Kröger, K. Gutensohn, Christoph Wagener, Michael Neumaier, AR Zander   +8 more
openalex   +1 more source

Assessing the interaction of the UCP system and fatty acids on epicardial adipose tissue mitochondrial respiration

European Journal of Clinical Investigation, EarlyView.
Epicardial adipose tissue (EAT) demonstrates higher mitochondrial activity than subcutaneous fat (SAT), particularly in NADH‐ and FAO‐linked oxidative phosphorylation (OXPHOS). While EAT expresses more UCP1, its inhibition by GDP minimally affects respiration, especially in FAO pathways, suggesting UCP1‐independence. Diabetes mellitus (DM) and coronary
Diana Santos, Ana Burgeiro, Ana Catarina R. G. Fonseca, Cândida Dias, Teresa Cunha‐Oliveira, Aryane Oliveira, João Laranjinha, António Canotilho, Gonçalo Coutinho, David Prieto, Pedro Antunes, Manuel Antunes, Eugenia Carvalho   +12 more
wiley   +1 more source

A Patient with COVID-19 Presenting a False-Negative Reverse Transcriptase Polymerase Chain Reaction Result. [PDF]

Korean J Radiol, 2020
Chen Z, Li Y, Wu B, Hou Y, Bao J, Deng X.   +5 more
europepmc   +1 more source