Results 91 to 100 of about 760,511 (339)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Remarks on the Logic of Irreversible Actions [PDF]
KOME: An International Journal of Pure Communication Inquiry, 2014 This paper proposes a logical system in which reversible and irreversible processes could be uniformly handled. This attempt originates in the observation that the question of reversibility not essentially emerges in logic, nor yet in temporal logic in ...
Márton Demeter
doaj
Spatial Correlation in Matter Wave Interference as a Measure of Decoherence, Dephasing and Entropy
, 2017 The loss of contrast in double-slit electron-diffraction due to dephasing and decoherence processes is studied. It is shown that the spatial correlation function of diffraction patterns can be used to distinguish between dephasing and decoherence.
Batelaan, Herman +2 more
core +1 more source
Reversibility of the effects of natalizumab on peripheral immune cell dynamics in MS patients
Neurology, 2017 Objective: To characterize the reversibility of natalizumab-mediated changes in pharmacokinetics/pharmacodynamics in patients with multiple sclerosis (MS) following therapy interruption. Methods: Pharmacokinetic/pharmacodynamic data were collected in the
T. Plavina +20 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The Role of Semantic Relations in the Creation of Metonymic Mappings
Miscelánea: A Journal of English and American Studies, 2001 In this paper I argue that the set of semantic relations put forward for the construction of propositional meaning by Ruiz de Mendoza (1996) can also be used to define the kinds of relationship that are established between the source and target domains ...
Olga Isabel Díaz Velasco
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Reversibility Violation in the Hybrid Monte Carlo Algorithm
, 2018 We investigate reversibility violations in the Hybrid Monte Carlo algorithm. Those violations are inevitable when computers with finite numerical precision are being used.
Urbach, Carsten
core +1 more source
Insights into the reversibility of aluminum graphite batteries
, 2017 Herein we report a novel study on the reaction mechanism of non-aqueous aluminum/graphite cell chemistry employing 1-ethyl-3-methylimidazolium chloride:aluminum trichloride (EMIMCl:AlCl3) as the electrolyte.
G. Elia +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source