Results 71 to 80 of about 80,273 (281)

AN ASSESSMENT OF CIVIL-MILITARY RELATIONS AND ITS IMPLICATIONS ON NIGERIA'S NATIONAL SECURITY

International Studies Journal, 2022
This paper attempts to trace the background to the sore relationship between the military and the civilian population. As this has continued to undermine the cordial civil-military relations in bordering on Nigeria's national security.
Uti Harrison Onyeka, Ubong Ituen Ituen
doaj  

Data Protection Under Review of Constitutional Court: Administrative Databases Directly Accessible to Public Authorities

TalTech Journal of European Studies
Abstract The development and use of administrative databases accelerate administrative and sometimes even criminal proceedings within public authorities. However, the increased data storage and free circulation of data pose a challenge to the protection of personal data and, thus, to the privacy of individuals.
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

State Anti-Crisis Management:the Age of the Formation of a New Model(Review of the Monograph of the Collective of the Authors of the MGIMO Russian Ministry of Foreign Affairs, under the General Editorship of Professor E. V. Okhotskiy «Public Administration in the Conditions of Crisis and Sanctionary Constraints: Domestic and Foreign Experience».M.: MGIMO-University Publishers, 2017. 889 p.)

Russian Journal of Legal Studies, 2018
The monograph «Public Administration in the Conditions of Crisis and Sanctionary Constraints: Domestic and Foreign Experience» touches upon the need for the operational development of concepts and mechanisms for studying, assessing, forecasting and sequential overcoming of actual crisis manifestations, especially the geopolitical crisis that began with
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

THE POTENTIALS AND LIMITATIONS OF TAX DISPUTE PREVENTION AND ALTERNATIVE RESOLUTION MECHANISMS

Zbornik Pravnog Fakulteta Sveučilišta u Rijeci, 2018
This paper deals with prevention and alternative dispute resolution (ADR) in tax matters, particularly in the light of the specific nature of administrative relations, which also include tax procedures. Given the involvement of stakeholders, ADR benefits
Polonca Kovač
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source