Results 81 to 90 of about 2,052,475 (288)
BMC Neuroscience, 2021 Background Men and women show differences in sensitivity to reward and punishment, which may impact behavior in health and disease. However, the neural bases of these sex differences remain under-investigated.
Isha Dhingra +5 more
doaj +1 more source
Heightened sensitivity to reward and punishment in anorexia nervosa [PDF]
International Journal of Eating Disorders, 2011 AbstractObjective:The objective of this study is to test whether females with anorexia nervosa (AN) have increased sensitivity to punishing or rewarding stimuli, behaviors that could drive high self‐control and anxious, avoidant behaviors.Method:Sixty‐four females completed the study: 33 control females (CFs, mean age 19.7 years) and 31 females with AN
Leah M, Jappe +7 more
openaire +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Neural reward and punishment sensitivity in cigarette smokers [PDF]
Drug and Alcohol Dependence, 2014 Nicotine addiction remains a major public health problem but the neural substrates of addictive behavior remain unknown. One characteristic of smoking behavior is impulsive choice, selecting the immediate reward of smoking despite the potential long-term negative consequences.
Geoffrey F, Potts +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Sensitivity and uncertainty analysis of Markov-reward models [PDF]
IEEE Transactions on Reliability, 1995 Markov-reward models are often used to analyze the reliability and performability of computer systems. One difficult problem therein is the quantification of the model parameters. If they are available, e.g., from measurement data collected by manufacturers, they are: (a) generally regarded as confidential; and (b) difficult to access.
Haverkort, Boudewijn R.H.M. +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
A Mouse-Tracking Paradigm for Value-Driven Attentional Capture
Behavioral SciencesReward learning is fundamental to adaptive behavior and exhibits substantial individual variability linked to addiction and other psychiatric conditions.
Yitong Chen +4 more
doaj +1 more source
, 2013 Reward sensitivity, or the tendency to engage in motivated approach behavior in the presence of rewarding stimuli, may be a contributory factor for vulnerability to disinhibitory behaviors.
Paola Fuentes +12 more
core +1 more source