Results 101 to 110 of about 68,233 (207)

20(S)-Ginsenoside Rh2 inhibits hepatocellular carcinoma by suppressing angiogenesis and the GPC3‐mediated Wnt/β‑catenin signaling pathway

Acta Biochimica et Biophysica Sinica
20(S)-Ginsenoside Rh2 has significant anti-tumor effects in various types of cancers, including human hepatocellular carcinoma (HCC). However, its molecular targets and mechanisms of action remain largely unknown.
Xu Linfei, Li Jing, Hou Ningning, Han Fang, Sun Xiaodong, Li Qinying   +5 more
doaj   +1 more source

Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer

Molecular Medicine
Background Ginsenoside Rh2 (G-Rh2), a steroidal compound extracted from roots of ginseng, has been extensively studied in tumor therapy. However, its specific regulatory mechanism in non-small cell lung cancer (NSCLC) is not well understood.
Xiyu Liu, Jingjing Li, Qingqing Huang, Mingming Jin, Gang Huang   +4 more
doaj   +1 more source

Ginsenoside Rh2 alleviates inflammatory response and enhances motor function recovery in spinal cord injury mice via the ROS/MAPK14 signaling pathway

Journal of Ginseng Research
Background: Inhibiting inflammation in nervous system is a vital part of treating for spinal cord injury (SCI). Compounds originating from plants can decrease the damage in the spinal cord for recovering the function of nerve and interrupting the ...
Yanlan Wu, Fangming Song, Xiuwei Tan, Jin Huang, Junliang Lu, Baihui Yang, Fang Fang, Xiaoxia Ye, Laoyi Geer, Fengxin Li, Qian Wei, Xuefeng Lu, Jiake Xu, Jie Jiang, Yiji Su   +14 more
doaj   +1 more source

20(S)-Ginsenoside Rh2 overcomes gemcitabine resistance in pancreatic cancer by inhibiting LAMC2-Modulated ABC transporters

Journal of Advanced Research
Introduction: Gemcitabine (GEM) is the first-line drug for pancreatic ductal adenocarcinoma (PDAC), but drug resistance severely restricts its chemotherapeutic efficacy. Laminin subunit γ2 (LAMC2) plays a crucial role in extracellular matrix formation in
Yulin Wu, Juan Zhang, Yuanyang Tian, William Chi Shing Cho, Hong-Xi Xu, Zhi-Xiu Lin, Yan-Fang Xian   +6 more
doaj   +1 more source

Enhanced anti-glioma activity of annonaceous acetogenins based on a novel liposomal co-delivery system with ginsenoside Rh2

Drug Delivery
Annonaceous acetogenins (ACGs) have potent anti-tumor activity, and the problems of their low solubility, hemolysis, and in vivo delivery have been solved by encapsulation into nanoparticles.
Hui Ao, Huizhu Song, Jing Li, Xiangtao Wang   +3 more
doaj   +1 more source

Enantioselective Synthesis of Spirolactones and Spirolactams Under Low Catalyst Loadings. [PDF]

J Am Chem Soc
Saito T, Navarro A, Davies HML.
europepmc   +1 more source

Research Progress on Anticancer Mechanism of Ginsenoside Regulating Tumor Microenvironment. [PDF]

Curr Issues Mol Biol
Liu T, Li W, Liu D, Xue B.
europepmc   +1 more source

Remote Stereocontrol in Aryl/Alkyl C-H Insertion Reactions of Rhodium Carbenes: Assembly of Pseudorigidols A and B. [PDF]

Org Lett
Ung L, Dishman SN, Zhang S, Fettinger JC, Shaw JT.   +4 more
europepmc   +1 more source

Visual pigments of basal lineages of bony fishes support independent ecological shifts from a shallow marine to a freshwater niche. [PDF]

Evol Lett
Cui Y, Li N, Chen H, Xing L, Xie Y, Xie Y, Ma M, Zhao J, Nan W, Lei L, Wang K, Rossiter SJ, Liu Y.   +12 more
europepmc   +1 more source

Entrainment profile of flies with only Rh2 and no Hiscl1 or flies with only Rh2 and no ort

Entrainment profile of flies with only Rh2 and no Hiscl1 or flies with only Rh2 and no ...
openaire   +1 more source