Results 61 to 70 of about 4,902 (179)

Characterization of Novel Rhabdoviruses in Chinese Bats

Viruses, 2021
Bats, the second largest order of mammals worldwide, harbor specific characteristics such as sustaining flight, a special immune system, unique habits, and ecological niches.
Dong-Sheng Luo, Bei Li, Xu-Rui Shen, Ren-Di Jiang, Yan Zhu, Jia Wu, Yi Fan, Hervé Bourhy, Ben Hu, Xing-Yi Ge, Zheng-Li Shi, Laurent Dacheux   +11 more
doaj   +1 more source

Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley   +1 more source

Genome Characterization of Bird-Related Rhabdoviruses Circulating in Africa

Viruses, 2021
Rhabdoviridae is the most diverse family of the negative, single-stranded RNA viruses, which includes 40 ecologically different genera that infect plants, insects, reptiles, fishes, and mammals, including humans, and birds.
Dong-Sheng Luo, Zhi-Jian Zhou, Xing-Yi Ge, Hervé Bourhy, Zheng-Li Shi, Marc Grandadam, Laurent Dacheux   +6 more
doaj   +1 more source

VHSV and IHNV in the Environment: Assessment and Comparison of eRNA‐Based Methods for Detection in Aquaculture

Environmental DNA, Volume 8, Issue 1, January–February 2026.
VHSV and IHNV molecular detection in environmental samples was tested in controlled infection trials. We show that, in water, detected viral eRNA copies correlate with infectious particle numbers. After comparison of viral concentration methods from water, we demonstrate the feasibility of filter‐based eRNA detection in IHNV‐positive aquaculture farms.
Giulia Zarantonello, Dagoberto Sepúlveda Araneda, Niccolò Vendramin, Andrea Marsella, Niels Lorenzen, Argelia Cuenca   +5 more
wiley   +1 more source

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota‐Targeted Interventions

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Qiong Zhao, Jianzhong Shao, Ye Chen, Hangjun Zhang, Lee Seong Wei   +4 more
wiley   +1 more source

In Vitro and In Vivo Toxicity and Antiviral Activity of Rhein Derivatives Against Nervous Necrosis Virus

Aquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
ABSTRACT Rhein has been demonstrated to exhibit antiviral activity against nervous necrosis virus (NNV). As rhein coexists in plants with various structurally analogous natural derivatives and may acquire improved biochemical properties through chemical modification, this study investigated the potential of several natural and synthetic derivatives for
Zhiqing Tian, Shuifang Zhu, Jialong Hu, Yaguang Zhu, Fan Jiang, Haolong Cong   +5 more
wiley   +1 more source

Early‐Stage Adhesion Dynamics of Viral Hemorrhagic Septicemia Virus in Olive Flounder, Paralichthys olivaceus

Journal of Fish Diseases, Volume 48, Issue 12, December 2025.
ABSTRACT Viral hemorrhagic septicemia virus (VHSV) is a major pathogen in olive flounder (Paralichthys olivaceus) aquaculture, leading to high mortality rates and significant economic losses. Recurrent outbreaks underscore the need for a deeper understanding of the early‐stage adhesion and infection mechanisms of VHSV.
Su‐Young Yoon, Yo‐Seb Jang, Soo‐Jin Kim, Myung‐Joo Oh   +3 more
wiley   +1 more source

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

mBio, 2018
RNA viruses that replicate in the cell cytoplasm typically concentrate their replication machinery within specialized compartments. This concentration favors enzymatic reactions and shields viral RNA from detection by cytosolic pattern recognition ...
Bianca S. Heinrich, Zoltan Maliga, David A. Stein, Anthony A. Hyman, Sean P. J. Whelan   +4 more
doaj   +1 more source

Bumble Bees and Honey Bees on Islands Harbour Reduced Viral Species Richness, Yet Honey Bee Populations Are Dominated by a Deformed Wing Virus Recombinant

Molecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Pollinators harbour diverse RNA viromes that play a vital role in their health. Yet, factors that shape viral communities are often unclear. The European honey bee (Apis mellifera) is experiencing a viral epidemic since the emergence of the parasitic mite Varroa destructor (varroa) introduced vector‐borne transmission, which has also been ...
Jana Dobelmann, Lena Wilfert
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, Volume 599, Issue 21, Page 3012-3028, November 2025.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source