Results 71 to 80 of about 9,342 (206)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Des alevins de brochet âgés de 10 jours à 2 mois ont été soumis à l'infection expérimentale par 4 souches de virus de salmonidés (NPI, NHI, SHV types 1 et 3) et par le rhabdovirus de la perche . Le virus de la NPI a provoqué une mortalité de 74% chez des
DORSON M. +3 more
doaj +1 more source
Characterization and application of monoclonal antibodies against turbot (Scophthalmus maximus) rhabdovirus [PDF]
Five monoclonal antibodies (mAbs), 1G8, 1H9, 2D2, 2D3, and 2F5, against Scophthalmus maximus rhabdovirus (SMRV) were prepared. Characterization of the mAbs included indirect enzyme-linked immunosorbent assay, isotyping, viral inhibition assay ...
Li, Zheng-Qiu +3 more
core +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Taxonomy of the order Mononegavirales : update 2016 [PDF]
In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera
Afonso, Claudio L. +82 more
core +1 more source
ABSTRACT Some mycoviruses cause hypovirulence in fungi, but the effects often vary among different host strains. Heterobasidion partitiviruses 13‐an1 and 15‐pa1 (HetPV13‐an1 and HetPV15‐pa1) have been associated with strain‐specific and variable hypovirulence of Heterobasidion annosum, but variation in phenotypic effects of HetPV15‐pa1 or the ...
Elina Roininen +3 more
wiley +1 more source
[1] Prevention and Treatment of Diseases Caused By Fish Pathogens [PDF]
This chapter describes methods to prevent and/or protect fish from infectious diseases. Chemotherapy using antimicrobial agents and criteria is effective but users should pay attention to avoid the increases of multiple drug resistant strains of fish ...
Jung Tae-Sung +10 more
core +1 more source
Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati +5 more
wiley +1 more source
Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments
RNA viruses that replicate in the cell cytoplasm typically concentrate their replication machinery within specialized compartments. This concentration favors enzymatic reactions and shields viral RNA from detection by cytosolic pattern recognition ...
Bianca S. Heinrich +4 more
doaj +1 more source

