Autocrine stimulation of rhadinovirus-transformed T cells by the chemokine CCL1/I-309 [PDF]
Oncogene, 2004 The rhadinovirus herpesvirus saimiri transforms human T lymphocytes to stable growth in culture. Besides the viral oncogenes stpC and tip, little is understood about the transformation process at the cellular level. To identify cellular factors that might contribute to growth transformation, we compared cellular gene expression in pairs of herpesvirus ...
Gültekin, Tamgüney +2 more
openaire +2 more sources
Pathogens, 2017 RTA, the viral Replication and Transcription Activator, is essential for rhadinovirus lytic gene expression upon de novo infection and reactivation from latency.
Alexis L. Santana +8 more
doaj +1 more source
Microtubule- and Dynein-Dependent Nuclear Trafficking of Rhesus Rhadinovirus in Rhesus Fibroblasts [PDF]
Journal of Virology, 2012 ABSTRACT We investigated the role of microtubules in rhesus rhadinovirus (RRV) nuclear trafficking in rhesus fibroblasts. Intact microtubules and microtubule dynamics are required for RRV trafficking to perinuclear regions. RRV trafficking was reduced by an inhibitor of the dynein motor and overexpression of dynamitin.
Wei, Zhang +2 more
openaire +2 more sources
A conserved Eph family receptor-binding motif on the gH/gL complex of Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus. [PDF]
PLoS Pathogens, 2018 Kaposi's sarcoma-associated herpesvirus (KSHV) is a human oncogenic virus associated with Kaposi's sarcoma and two B-cell malignancies. The rhesus monkey rhadinovirus (RRV) is a virus of nonhuman primates that is closely related to KSHV.
Anna K Großkopf +6 more
doaj +1 more source
Pathogens, 2012 As obligate intracellular pathogens, viruses depend on the host cell machinery to complete their life cycle. Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus causally linked to the development of Kaposi’s sarcoma and several other ...
Wei Zhang, Shou-Jiang Gao
doaj +1 more source
Frontiers in Immunology, 2023 IntroductionBovine herpesvirus 4 (BoHV-4) is a bovine Rhadinovirus not associated with a specific pathological lesion or disease and experimentally employed as a viral vector vaccine.
Seok-Chan Park +10 more
doaj +1 more source
Activation of Lymphocyte Signaling by the R1 Protein of Rhesus Monkey Rhadinovirus [PDF]
Journal of Virology, 2000 ABSTRACTRhesus monkey rhadinovirus(RRV) is a gamma-2 herpesvirus that exhibits a considerable degree of similarity to the humanKaposi's sarcoma-associated herpesvirus(KSHV). The R1 protein of RRV is distantly related to the K1 protein of KSHV, and R1, like K1, can contribute to cell growth transformation.
B, Damania +3 more
openaire +2 more sources
Cryo-electron tomography of Kaposi\u27s sarcoma-associated herpesvirus capsids reveals dynamic scaffolding structures essential to capsid assembly and maturation. [PDF]
, 2008 Kaposi\u27s sarcoma-associated herpesvirus (KSHV) is a recently discovered DNA tumor virus that belongs to the gamma-herpesvirus subfamily. Though numerous studies on KSHV and other herpesviruses, in general, have revealed much about their multilayered ...
Deng, Binbin +3 more
core +1 more source
Location and Dynamics of the Immunodominant CD8 T Cell Response to SIVΔnef Immunization and SIVmac251 Vaginal Challenge [PDF]
, 2013 Live-attenuated SIV vaccines (LAVs) have been the most effective to date in preventing or partially controlling infection by wild-type SIV in non-human primate models of HIV-1 transmission to women acting by mechanisms of protection that are not well ...
Haase, Ashley T. +12 more
core +13 more sources
First description of a herpesvirus infection in genus Lepus.
PLoS ONE, 2020 During the necropsies of Iberian hares obtained in 2018/2019, along with signs of the nodular form of myxomatosis, other unexpected external lesions were also observed.
F A Abade dos Santos +8 more
doaj +1 more source