Results 21 to 30 of about 125,675 (280)
Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway
Journal of Experimental & Clinical Cancer Research, 2019 Background Rhein is a lipophilic anthraquinone extensively found in medicinal herbs. Emerging evidence suggests that rhein has significant antitumor effects, supporting its potential use as an antitumor agent.
Lehe Yang +9 more
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International Journal of Analytical Chemistry, 2020 Rhein is an important quality-control marker of Rheum officinale. The aim of this study was to develop an indirect competitive enzyme-linked immunosorbent assay (icELISA) for rhein detection, which acts as a powerful tool for quality control and proper ...
Min Chen +6 more
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Anthraquinone Rhein Exhibits Antibacterial Activity against Staphylococcus aureus
Applied Sciences, 2022 Staphylococcus aureus (S. aureus) represents an important pathogen of clinical relevance, causing a wide variety of symptoms. The broad distribution of multidrug-resistant strains necessarily demands new antibacterial agents for the treatment of S ...
Federica Dell’Annunziata +9 more
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Journal of Medical SciencesBackground Enterovirus 71 (EV71) is one of the most prevalent pathogens responsible for hand, foot, and mouth disease in the Asia-Pacific region. Severe EV71 infections can be fatal in children under the age of 5. As of now, there are no proven anti-EV71
Zheng-Zong Lai +2 more
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Agronomy, 2022 The greenness indices of literature analytical procedures for the simultaneous measurement of rhein and aloe-emodin have not been determined. As a consequence, the first goal of this study was to design and validate a sensitive and sustainable reverse ...
Mohammed H. Alqarni +5 more
doaj +1 more source
Rhein targets macrophage SIRT2 to promote adipose tissue thermogenesis in obesity in mice
Communications BiologyRhein, a component derived from rhubarb, has been proven to possess anti-inflammatory properties. Here, we show that rhein mitigates obesity by promoting adipose tissue thermogenesis in diet-induced obese mice.
Ruo-Nan Zhou +14 more
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Frontiers in Pharmacology, 2020 Objectives: The interaction between the components of traditional Chinese medicine (TCM) is an important basis for their synergy. Rhein and curcumin exert various pharmacological activities, including anti-tumour, anti-inflammatory, antioxidant, anti ...
Xiaoying He +7 more
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BMC Complementary Medicine and Therapies, 2022 Background The Sheng-ji Hua-yu (SJHY) formula is a quite effective Traditional Chinese Medicines (TCM) in the treatment of delayed diabetic wounds. Previous research has shown that the SJHY formula has significant anti-inflammatory and wound-healing ...
Ning Xu +10 more
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Molecules, 2022 Currently, both acute kidney injury (AKI) and chronic kidney disease (CKD) are considered to be the leading public health problems with gradually increasing incidence rates around the world.
Yanna Zhu +7 more
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Human intestinal Bacteroides spp. RHEIN-I and RHEIN-II capable of transforming rhein to rheinanthrone, induce rhein-dependent diarrhea in rats [PDF]
, 2001 Two rhein-metabolizing bacteria were isolated from human feces. The biochemical and morphological characteristics of both isolates were typical of Bacteroides spp. and named strains RHEIN-I and RHEIN-II, respectively. Rhein was effectively metabolized to
Akao Teruaki +3 more
core +1 more source