Organ Transplantation: Current Status, Challenges, and Future Prospects
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
Incidence of Post-Sedation Emesis in Cynomolgus (<i>Macaca fascicularis</i>) and Rhesus (<i>Macaca mulatta</i>) Macaques, and Evaluation of Prophylactic Antiemetic Efficacy. [PDF]
Coley R +3 more
europepmc +1 more source
Bernard‐Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient
This study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Mohamed Lemine Salem +2 more
wiley +1 more source
A decreased proportion of naïve MAIT cells is associated with the incomplete immune reconstitution in antiretroviral therapy-treated HIV-1 patients. [PDF]
Jia J +13 more
europepmc +1 more source
We report a novel IBA57 variant in a pediatric case, with pathogenicity confirmed through familial segregation analysis, Sanger sequencing, 3D protein modeling, and evolutionary conservation studies. Mitochondrial complex activity assays demonstrated functional impairment. A comprehensive review of literature further elucidates the genotypic‐phenotypic
Jia Xu +5 more
wiley +1 more source
Determining A1C Normal Values in Rhesus Macaques (Macaca mulatta). [PDF]
Dufour JP +3 more
europepmc +1 more source
Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor
Abstract CD1d, a non‐classical immunoreceptor, plays a central role in lipid antigen presentation to a variety of T cell types. Despite the widespread use of detergents to measure and manipulate lipid/CD1d interactions in vitro, in situ, and in vivo, the molecular basis by which detergents influence the stability of CD1d and its lipid binding ...
Uri Z. Miles +2 more
wiley +1 more source
Paternity testing for crab-eating macaques and rhesus macaques using microsatellite markers. [PDF]
Yuan Y +10 more
europepmc +1 more source
ABSTRACT Unarguably, malware and their variants have metamorphosed into objects of attack and cyber warfare. These issues have directed research focus to modeling infrastructural settings and infection scenarios, analyzing propagation mechanisms, and conducting studies that highlight optimized remedial measures.
Chukwunonso Henry Nwokoye
wiley +1 more source

