Results 21 to 30 of about 166,738 (337)
SARS-CoV-2 Omicron BA.1 and BA.2 are attenuated in rhesus macaques as compared to Delta
Science Advances, 2022 Since the emergence of SARS-CoV-2, five different variants of concern (VOCs) have been identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the human population, such as preexisting immunity, comparing severity of disease
N. van Doremalen +20 more
semanticscholar +1 more source
Journal of Neuroscience Research, Volume 101, Issue 2, Page 263-277, February 2023., 2023 Substantia nigra (SN) hyperechogenicity, viewed with transcranial ultrasound, is a risk marker for Parkinson's disease. SN hyperechogenicity in healthy older adults is associated with changes in the excitability of specific motor cortical circuitry. These changes are unrelated to glutamate levels in the pre‐supplementary motor area (pre‐SMA).
Gabrielle Todd +18 more
wiley +1 more source
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques
Science, 2020 Immunity from reinfection One of the many open questions about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is whether an individual who has cleared the virus can be infected a second time and get sick. Chandrashekar et al.
Wei Deng +26 more
semanticscholar +1 more source
ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques
bioRxiv, 2020 Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 20191,2 and is responsible for the COVID-19 pandemic3. Vaccines are an essential countermeasure urgently needed to control the pandemic4.
N. van Doremalen +34 more
semanticscholar +1 more source
A little less aggregation a little more replication: Viral manipulation of stress granules
WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023 Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source
CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies
WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023 CRISPR‐Cas9 gene‐editing technology enables the rapid generation of animal models for Duchenne muscular dystrophy research and has potential to be developed as CRISPR therapy for the long lasting genetic correction of causal mutations. Abstract CRISPR gene‐editing technology creates precise and permanent modifications to DNA.
Yu C. J. Chey +4 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2019 We sequenced the complete mitochondrial genome (mitogenome) of Siberian Roe Deer, Capreolus pygargus, in China by the shotgun genome-skimming methods. The mitogenome of C. pygargus is totally 16,353 bp in length and contains 13 protein-coding genes (PCGs)
Tao Li +3 more
doaj +1 more source
Mechanisms underlying cognitive bias in nonhuman primates.
Animal Behavior and Cognition, 2017 Recent research in nonhuman animals highlights the exciting possibility that performance on cognitive bias tasks might indirectly measure an individual’s subjective, affective state.
Bonnie M. Perdue
doaj +1 more source
BMJ, 1979 1 Roberts, 1 F et al, British Medical Journal, 1979, 1, 296. 2 Robson, J R K, Pediatrics, 1974, 53, 326. 8 Berkelhamer, J E, Thorpe, F K, and Cobbs, S, American Journal of Diseases of Children, 1975, 129, 1240. 4 Barness, L A, et al, Pediatrics, 1977, 59, 460. 5 Robson, J R K, P?diatrie Clinics of North America, 1977, 24, 189.
openaire +3 more sources
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques
Cell Research, 2020 The 2019 novel coronavirus (SARS-CoV-2) outbreak is a major challenge for public health. SARS-CoV-2 infection in human has a broad clinical spectrum ranging from mild to severe cases, with a mortality rate of ~6.4% worldwide (based on World Health ...
Chao Shan +25 more
semanticscholar +1 more source