Results 91 to 100 of about 65,503 (295)

Bottom‐Up Ice Growth Geometry Attenuates Shear Stress and Improves the Cryopreservation of Hematopoietic Stem/Progenitor Cells Under Low DMSO Concentrations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves, Pedro Sena Rego, Marta H. G. Costa, Isabel Bogalho, Andreia Duarte, Claúdia L. da Silva, Frederico Castelo Ferreira, Vitor Geraldes, Miguel A. Rodrigues   +8 more
wiley   +1 more source

Auditory Rehabilitation in Rhesus Macaque Monkeys (Macaca mulatta) with Auditory Brainstem Implants

Chinese Medical Journal, 2015
Background: The auditory brainstem implants (ABIs) have been used to treat deafness for patients with neurofibromatosis Type 2 and nontumor patients. The lack of an appropriate animal model has limited the study of improving hearing rehabilitation by the
Zhen-Min Wang, Zhi-Jun Yang, Fu Zhao, Bo Wang, Xing-Chao Wang, Pei-Ran Qu, Pi-Nan Liu   +6 more
doaj   +1 more source

The impact of urbanisation on social behaviour: a comprehensive review

Biological Reviews, EarlyView.
ABSTRACT Urbanisation is a key driver of global environmental change and presents animals with novel stressors and challenges. It can fundamentally influence social behaviour and has the potential to reshape within‐ and between‐species social interactions. Given the role of social behaviour in reproductive fitness and survival, understanding how social
Avery L. Maune, Barbara A. Caspers, Isabel Damas‐Moreira   +2 more
wiley   +1 more source

Systemic lupus erythematosus in a rhesus macaque [PDF]

Arthritis & Rheumatism, 1993
AbstractWe describe the clinical course and histopathologic findings in a rhesus macaque (Macaca mulatta) which developed a systemic inflammatory disorder resembling systemic lupus erythematosus (SLE). The manifestations of the SLE included antinuclear antibody, hemolytic anemia, membranoproliferative glomerulonephritis, and arthritis. To our knowledge,
S T, Anderson, E C, Klein
openaire   +2 more sources

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Evolutionary distance of amino acid sequence orthologs across macaque subspecies: identifying candidate genes for SIV resistance in Chinese rhesus macaques. [PDF]

PLoS ONE, 2015
We use the Reciprocal Smallest Distance (RSD) algorithm to identify amino acid sequence orthologs in the Chinese and Indian rhesus macaque draft sequences and estimate the evolutionary distance between such orthologs.
Cody T Ross, Morteza Roodgar, David Glenn Smith   +2 more
doaj   +1 more source

Not just ‘super‐predators': human behaviour shapes wildlife behavioural responses across avoidance, tolerance and attraction

Oikos, EarlyView.
Humans are thought to have a disproportionately negative impact on wildlife and are viewed by some as the ultimate ‘super predator'. This view implies that wild animals perceive humans primarily as predators. However, a growing body of evidence shows that wildlife can have remarkable tolerance for, or even attraction to, humans.
Friederike Zenth, Daniel T. Blumstein, Luca Corlatti, Mengxi Kou, Sebastian Schwegmann, Farina Sooth, Ilse Storch, Manisha Bhardwaj   +7 more
wiley   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

VIEW, EarlyView.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

Nonhuman Primate Model of Oculocutaneous Albinism with TYR and OCA2 Mutations

Research, 2020
Human visual acuity is anatomically determined by the retinal fovea. The ontogenetic development of the fovea can be seriously hindered by oculocutaneous albinism (OCA), which is characterized by a disorder of melanin synthesis.
Kun-Chao Wu, Ji-Neng Lv, Hui Yang, Feng-Mei Yang, Rui Lin, Qiang Lin, Ren-Juan Shen, Jun-Bin Wang, Wen-Hua Duan, Min Hu, Jun Zhang, Zhan-Long He, Zi-Bing Jin   +12 more
doaj   +1 more source