Results 81 to 90 of about 11,563 (171)

A Pilot Placebo‐Controlled Randomized Trial of Repeated High‐Dose Intravenous Magnesium Sulphate and High‐Dose Nebulized Budesonide for Severe Asthma in the Paediatric Emergency Department

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Determine if high‐dose intravenous magnesium with/without nebulized budesonide for children with acute severe asthma is safe and reduces time to medical readiness for discharge compared to standard intravenous magnesium. Methods Either 2 doses of intravenous magnesium or 1 dose and placebo, each with/without high‐dose nebulized ...
Khalid Alansari, Fatin Abou Moussa, Hadi Abu Rasheed, Bruce L. Davidson, Khalid Yousif Ibrahim, Mahmoud Alrifaai   +5 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Infection and Coinfection of Human Rhinovirus C in Stem Cell Transplant Recipients

Clinical and Developmental Immunology, 2013
In 54 adult stem cell transplant recipients, the presence and persistence of human rhinoviruses (including the novel lineage C) were evaluated by molecular detection and phylogenetic analysis, independently from respiratory symptoms. In the same group of
Filippo Canducci, Maurizia Debiaggi, Elisa Rita Ceresola, Michela Sampaolo, Emilio Paolo Alessandrino, Roberto Brerra, Aurora Piazza, Massimo Clementi   +7 more
doaj   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

Incidental Detection of Respiratory Viruses in Lung Transplant Donor‐Recipient Pairs: Exploratory Associations With Clinical Outcomes in a Post Hoc Analysis

Transplant Infectious Disease, EarlyView.
In 53 lung transplant donor‐recipient pairs, community‐acquired respiratory viruses were incidentally detected by syndromic PCR in 13.2% of donor and 20.8% of recipient bronchoalveolar lavages, with exploratory, unadjusted signals towards longer hospitalization and chronic lung allograft dysfunction.
Andrea Lombardi, Letizia Corinna Morlacchi, Giulia Renisi, Lorenzo Rosso, Jacopo Fumagalli, Patrizia Bono, Ilaria Righi, Valeria Rossetti, Arianna Liparoti, Cecilia Azzarà, Davide Mangioni, Laura Alagna, Anna Celotti, Claudia Alteri, Chiara Abbruzzese, Annapaola Callegaro, Francesco Blasi, Giacomo Grasselli, Mario Nosotti, Alessandra Bandera   +19 more
wiley   +1 more source

Fatal Respiratory Infections Associated with Rhinovirus Outbreak, Vietnam

Emerging Infectious Diseases, 2012
During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0 ...
Le Thanh Hai, Vu Thi Ngoc Bich, Le Kien Ngai, Nguyen Thi Ngoc Diep, Phan Huu Phuc, Viet Pham Hung, Walter R. Taylor, Peter Horby, Nguyen Thanh Liem, Heiman F.L. Wertheim   +9 more
doaj   +1 more source

Rhinovirus in Adults With Severe Lower Respiratory Tract Infection: Incidental Carriage or Primary Pathogen? A Comparative Study Across Different Clinical Status Categories

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Rhinovirus (RV) is a recognized respiratory pathogen, but its role in severe lower respiratory tract infections (LRTI) in adults remains debated. The aim of the study was to investigate RV in different clinical status categories at Hospital Sao Paulo, a tertiary facility in Sao Paulo, Brazil.
Ana Helena Perosa, Klinger S. Faico‐Filho, Karen Pendeloski, Rodrigo Matheus, Nancy Bellei   +4 more
wiley   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Recurring Temporal Association Between Influenza A Epidemics and Subsequent Influenza B Dominance in Post‐Pandemic Korea, 2022−2026

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Post‐pandemic influenza dynamics have shown unusual patterns globally. We investigated the re‐emergence and recurrent seasonal dominance of influenza B in Korea across three post‐pandemic seasons (2022−2026). We analyzed 157 consecutive weeks of national sentinel surveillance data (K‐SenS, Korea Disease Control and Prevention Agency), covering
Yoon Lee, Yoonsun Yoon, Ji Eun Park, Won Keun Kim, Youn Young Choi, Yun‐Kyung Kim, Changmin Kang, Young Yoo, Young June Choe   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source