Results 61 to 70 of about 11,563 (171)

CHARACTERISTICS OF THE CAUSATIVE AGENTS OF ACUTE RESPIRATORY VIRAL INFECTIONS AND THE IMPORTANCE OF DISINFECTION MEASURES IN PREVENTING THEIR SPREAD

Детские инфекции (Москва), 2018
The article presents a review of the literature about the etiological structure of respiratory infections in the modern period, the role of viruses agrippinae etiology in the formation of severe diseases of the respiratory system and their stability in ...
L. V. Rubis
doaj   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

The prevalence of the human rhinoviruses and coronaviruses circulating in the Moscow region during 2007-2012

Вопросы вирусологии, 2015
The rhinoviruses and coronaviruses are the most common causative agents of the acute upper respiratory tract infection in humans. They include several species that vary in the pathogenicity, some causing severe respiratory tract diseases.
S. A. Lobodanov, I. S. Kiselev, Y. I. Ammour, A. E. Gorbalenya, E. C. J. Claas, V. V. Zverev, E. B. Faizuloev   +6 more
doaj  

Construction and characterization of an infectious cDNA clone of human rhinovirus A89

Heliyon
Rhinoviruses (RVs) are major causes of the common cold and are related to severe respiratory tract diseases, leading to a considerable economic burden and impacts on public health.
Hongwei Yang, Rui Zhu, Zhenhong Zhou, Hao Chen, Yuanyuan Wu, Dongqing Zhang, Che Liu, Ningshao Xia, Longfa Xu, Tong Cheng   +9 more
doaj   +1 more source

In Vivo Persistence of Human Rhinoviruses in Immunosuppressed Patients.

PLoS ONE, 2017
Several species of the genus Enterovirus cause persistent infections in humans. Human rhinovirus (HRV) infections are generally self-limiting but occasionally persistent infections have been described.
Ilka Engelmann, Anny Dewilde, Mouna Lazrek, Mathilde Batteux, Aminati Hamissi, Ibrahim Yakoub-Agha, Didier Hober   +6 more
doaj   +1 more source

Cations in Human Rhinoviruses [PDF]

, 1997
All known crystal structures of rhinoviruses have some uninterpreted electron density on their fivefold axes at a distance of about 152 ± 3 Å from the viral center.
KREMER, MARCIA J., ZHAO, RUI, ROSSMANN, MICHAEL G., HADFIELD, ANDREA T.   +3 more
core   +1 more source

Pathogenic Airway Bacteria and Local Immune Responses During Early‐Life Asthma‐Like Episodes

Allergy, EarlyView.
This study investigates how Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis associate with airway immune responses during early‐life asthma‐like episodes, and compare these responses between children with and without asthma.
Mathilde Bundgaard Svendsen, Tamo Sultan, Anton Kjellberg, Mathias Melgaard, Susanne Brix, Karen Krogfelt, Nilo Vahman, Ann‐Marie Malby Schoos, Jakob Stokholm, Bo Lund Chawes, Klaus Bønnelykke, Jonathan Thorsen, Julie Nyholm Kyvsgaard   +12 more
wiley   +1 more source

A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

Nature Communications, 2016
Existence of 150–170 serologically distinct human rhinoviruses (HRV) has hampered vaccine development for this human pathogen. Here, the authors show that a prime-boost regimen with an inactivated 50-valent HRV vaccine induces neutralizing antibody ...
Sujin Lee, Minh Trang Nguyen, Michael G. Currier, Joe B. Jenkins, Elizabeth A. Strobert, Adriana E. Kajon, Ranjna Madan-Lala, Yury A. Bochkov, James E. Gern, Krishnendu Roy, Xiaoyan Lu, Dean D. Erdman, Paul Spearman, Martin L. Moore   +13 more
doaj   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.

PLoS Biology, 2019
Rhino- and enteroviruses are important human pathogens, against which no antivirals are available. The best-studied inhibitors are "capsid binders" that fit in a hydrophobic pocket of the viral capsid.
Rana Abdelnabi, James A Geraets, Yipeng Ma, Carmen Mirabelli, Justin W Flatt, Aušra Domanska, Leen Delang, Dirk Jochmans, Timiri Ajay Kumar, Venkatesan Jayaprakash, Barij Nayan Sinha, Pieter Leyssen, Sarah J Butcher, Johan Neyts   +13 more
doaj   +1 more source