Results 171 to 180 of about 105,843 (252)

Unravelling the Intraspecific Variation in Drought Responses in Seedlings of European Black Pine (Pinus Nigra J.F. Arnold)

Plant, Cell &Environment, EarlyView.
ABSTRACT Understanding intraspecific variation in drought tolerance is essential for predicting the adaptive capacity of forest species under climate change. Yet, the molecular basis of this variation remains poorly understood in ecologically and economically important conifers.
Muhammad Ahmad, Almuth Hammerbacher, Clara Priemer, Albert Ciceu, Marta Karolak, Sonja Mader, Sanna Olsson, Johann Schinnerl, Sebastian Seitner, Selina Schöndorfer, Paula Helfenbein, Jakub Jez, Michaela Breuer, Ana Espinosa‐Ruiz, Teresa Caballero, Andrea Ganthaler, Stefan Mayr, Dominik K. Großkinsky, Stefanie Wienkoop, Silvio Schueler, Carlos Trujillo‐Moya, Marcela van Loo   +21 more
wiley   +1 more source

Ocular effects of Rho kinase (ROCK) inhibition: a systematic review. [PDF]

Eye (Lond)
Lin JB, Harris JM, Baldwin G, Goss D, Margeta MA.   +4 more
europepmc   +1 more source

Two proteins co‐expressed with photosynthetic regulators affect photosynthetic dynamics linked to changes in thylakoid pigment content and composition

Plant Biology, EarlyView.
Two factors identified by co‐expression analysis of photosynthetic regulators are described, which are involved in thylakoid pigment content and composition and, through their function, shape the dynamics of NPQ. Abstract Rapid fluctuations in light intensity require swift regulatory adjustments of photosynthesis. Although the major plant regulators of
J.‐M. Keller, F. Dinc, E. Kaiser, A. Zupok, B. A. Morris, T. von Bismarck, V. Correa Galvis, W. Thiele, D. M. Kramer, P. Jahns, M. A. Schöttler, U. Armbruster   +11 more
wiley   +1 more source

Effects of Ripasudil Hydrochloride Hydrate-Brimonidine Tartrate Fixed-Dose Combination Using Rho Kinase Inhibitor and Alpha2 Adrenergic Receptor Agonist on Aqueous Column in the Episcleral Vein: A Randomized, Double-Masked, Crossover Clinical Trial (ROCK Alpha-Aqua Study). [PDF]

J Clin Med
Suzuki M, Arimura S, Iwasaki K, Orii Y, Kakimoto H, Komori R, Yamamura S, Inatani M.   +7 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Rho Kinase (ROCK) Inhibitors in the Treatment of Glaucoma and Glaucoma Surgery: A Systematic Review of Early to Late Phase Clinical Trials. [PDF]

Pharmaceuticals (Basel)
Tan JK, Khaw PT, Henein C.
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy. [PDF]

Invest Ophthalmol Vis Sci
Quillen SE, Kimball EC, Ritter-Gordy KA, Du L, Yuan Z, Pease ME, Madhoun S, Nguyen TD, Johnson TV, Quigley HA, Pitha IF.   +10 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source