Results 181 to 190 of about 105,843 (252)

Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma. [PDF]

Curr Drug Targets
Wu J, Wei J, Chen H, Dang Y, Lei F.
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

The Role of Rho Kinase Inhibitors in Corneal Diseases. [PDF]

Drug Des Devel Ther
Futterknecht S, Chatzimichail E, Gugleta K, Panos GD, Gatzioufas Z.   +4 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

RhoA/rho kinase pathway activation in age-associated endothelial cell dysfunction and thrombosis. [PDF]

J Cell Mol Med
Palomo I, Wehinger S, Andrés V, García-García FJ, Fuentes E.   +4 more
europepmc   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

A Novel Single-Color FRET Sensor for Rho-Kinase Reveals Calcium-Dependent Activation of RhoA and ROCK. [PDF]

Sensors (Basel)
Mancini AE, Rizzo MA.
europepmc   +1 more source

Musculoskeletal and physiological responses to vortex wave stimulation in older adults

The Journal of Physiology, EarlyView.
Abstract figure legend We explored the acute physiological effects of a novel mechanical stimulus, vortex wave stimulation (VWS), in healthy older adults. Using deuterated water and serial skeletal muscle biopsies, we showed that VWS elevated integrated rates of myofibrillar, but not sarcoplasmic muscle protein synthesis, with no changes observed in ...
Alexander Waddell, Marie Korzepa, Archie E. Belfield, Ben Fry, Rickson C Mesquita, David Smith, Jonathan Quinlan, Leigh Breen   +7 more
wiley   +1 more source

Evaluation of Rho kinase inhibitor effects on neuroprotection and neuroinflammation in an ex-vivo retinal explant model. [PDF]

Acta Neuropathol Commun
Reboussin É, Bastelica P, Benmessabih I, Cordovilla A, Delarasse C, Réaux-Le Goazigo A, Brignole-Baudouin F, Olmière C, Baudouin C, Buffault J, Mélik Parsadaniantz S.   +10 more
europepmc   +1 more source

Cytoarchitecture of Breast Cancer Cells under Diabetic Conditions: Role of Regulatory Kinases-Rho Kinase and Focal Adhesion Kinase. [PDF]

Cancers (Basel)
Dutta D, Ziemke M, Sindelar P, Vargas H, Lim JY, Chandra S.   +5 more
europepmc   +1 more source