Results 61 to 70 of about 381,524 (309)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcus aureus and Encoded Virulence Factors

mSphere, 2016
Atopic dermatitis (AD) is an inflammatory skin condition strongly associated with Staphylococcus aureus colonization and infection. S. aureus strains shift in populations in ~10-year intervals depending on virulence factors. Shifts in S. aureus virulence
Joseph A. Merriman, Elizabeth A. Mueller, Michael P. Cahill, Lisa A. Beck, Amy S. Paller, Jon M. Hanifin, Peck Y. Ong, Lynda Schneider, Denise C. Babineau, Gloria David, Alexandre Lockhart, Keli Artis, Donald Y. M. Leung, Patrick M. Schlievert   +13 more
doaj   +1 more source

PORTFOLIO RHO-PRESENTATIVITY

International Journal of Theoretical and Applied Finance, 2017
Given an investment universe, we consider the vector [Formula: see text] of correlations of all assets to a portfolio with weights [Formula: see text]. This vector offers a representation equivalent to [Formula: see text] and leads to the notion of [Formula: see text]-presentative portfolio, that has a positive correlation, or exposure, to all assets.
TRISTAN FROIDURE, KHALID JALALZAI, YVES CHOUEIFATY   +2 more
openaire   +1 more source

Amblyopsis-Final-RHO

, 2012
nuclear RHO (rhodopsin), coding region, Nexus ...
Matthew Lance Niemiller (3265101), William D. Pearson (3265092), Near, Thomas J., Pearson, William D., James R. McCandless (3265095), Tillquist, Christopher R., Benjamin Minault Fitzpatrick (3250707), Niemiller, Matthew Lance, Reynolds, Robert Graham, Robert Graham Reynolds (3265089), Christopher R. Tillquist (3265098), Caddle, James, Thomas J. Near (3191996), Fitzpatrick, Benjamin Minault, James Caddle (3265086), McCandless, James R.   +15 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Data-Driven Modeling for Species-Level Taxonomic Assignment From 16S rRNA: Application to Human Microbiomes

Frontiers in Microbiology, 2020
With the emergence of next-generation sequencing (NGS) technology, there have been a large number of metagenomic studies that estimated the bacterial composition via 16S ribosomal RNA (16S rRNA) amplicon sequencing.
Ho-Jin Gwak, Mina Rho, Mina Rho
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fiftieth Anniversary Issue: The Pine Tree Sig, Rho Rho Chapter, Sigma Chi Fraternity [PDF]

, 1952
A special issue of The Pine Tree Sig, a publication of the Sigma Chi fraternity, Rho Rho Chapter, University of Maine. Cover title: Sigma Chi has been at Maine for 50 Years. Editor, Dick Shurman.
Sigma Chi Fraternity, Rho Rho Chapter
core  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source