Results 31 to 40 of about 161,318 (264)
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease [PDF]
Oncogene, 2013 The aberrant activity of Ras homologous (Rho) family small GTPases (20 human members) has been implicated in cancer and other human diseases. However, in contrast to the direct mutational activation of Ras found in cancer and developmental disorders, Rho GTPases are activated most commonly by indirect mechanisms in disease.
D R, Cook, K L, Rossman, C J, Der
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QCD factorizations in gamma* gamma* -> rho rho
, 2006 We calculate the lowest order QCD amplitude, i.e. the quark exchange contribution, to the forward production amplitude of a pair of longitudinally polarized $\rho$ mesons in the scattering of two virtual photons $\gamma^*(Q_1) \gamma^*(Q_2) \to \rho^0_L \rho^0_L$.
Pire, B. +3 more
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Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2012 Background The level of soluble vascular endothelial growth factor receptor 1 (sVEGFR1) is increased in sepsis and strongly associated with disease severity and mortality.
Ostrowski Sisse R +7 more
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The perturbative QCD factorization of $\rho \gamma^{\star} \to \rho$
, 2015 In this paper we firstly demonstrate step by step that the factorization hypothesis is valid at the next-to-leading order (NLO) for the exclusive process $\rho \gamma^{\star} \to \rho$ by employing the collinear factorization approach, and then extend this proof to the case of the $k_T$ factorization by taking into account the transversal momentum of ...
Zhang, Ya-lan +3 more
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Scientific Reports, 2022 Despite the extensive investigation on the stress and displacement distributions in tunnels, few have considered the influences of the damaged zone around a tunnel on the strength and stiffness parameters of the surrounding rock, including the gradual ...
Jinwang Li +4 more
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Rho Family GTPases and Rho GEFs in Glucose Homeostasis
Cells, 2021 Dysregulation of glucose homeostasis leading to metabolic syndrome and type 2 diabetes is the cause of an increasing world health crisis. New intriguing roles have emerged for Rho family GTPases and their Rho guanine nucleotide exchange factor (GEF ...
Polly A. Machin +3 more
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The Antigenicity of the Rho (Du) Blood Factor [PDF]
Blood, 1962 Abstract The antigenicity of the Rh variant Rho(Du) was investigated by the transfusion of 45 Rh negative (cde/cde) patients with 68 units of "low grade" Rho (Du) blood of the phenotypes Rho(ccDuee) or Rh2(ccDuE). The donor red cells had normal viability; none of the patients made antibodies to Rho(D) or Rho(Du).
PAUL J. SCHMIDT +2 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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